Multifactorial Inheritance
"Multifactorial Inheritance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phenotypic outcome (physical characteristic or disease predisposition) that is determined by more than one gene. Polygenic refers to those determined by many genes, while oligogenic refers to those determined by a few genes.
| Descriptor ID |
D020412
|
| MeSH Number(s) |
G05.420.590
|
| Concept/Terms |
Multifactorial Inheritance- Multifactorial Inheritance
- Inheritance, Multifactorial
- Inheritances, Multifactorial
- Multifactorial Inheritances
Polygenic Inheritance- Polygenic Inheritance
- Inheritance, Polygenic
- Inheritances, Polygenic
- Polygenic Inheritances
- Polygenic Traits
- Polygenic Trait
- Trait, Polygenic
- Traits, Polygenic
- Polygenic Characters
- Character, Polygenic
- Characters, Polygenic
- Polygenic Character
Oligogenic Inheritance- Oligogenic Inheritance
- Inheritance, Oligogenic
- Inheritances, Oligogenic
- Oligogenic Inheritances
- Oligogenic Traits
- Oligogenic Trait
- Trait, Oligogenic
- Traits, Oligogenic
|
Below are MeSH descriptors whose meaning is more general than "Multifactorial Inheritance".
Below are MeSH descriptors whose meaning is more specific than "Multifactorial Inheritance".
This graph shows the total number of publications written about "Multifactorial Inheritance" by people in this website by year, and whether "Multifactorial Inheritance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 2 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Multifactorial Inheritance" by people in Profiles.
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Polygenic architecture of rare coding variation across 394,783 exomes. Nature. 2023 Feb; 614(7948):492-499.
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Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease. Am J Hum Genet. 2021 03 04; 108(3):431-445.
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Large-scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease. Acta Neuropathol. 2020 09; 140(3):341-358.
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Overlapping genetic architecture between Parkinson disease and melanoma. Acta Neuropathol. 2020 02; 139(2):347-364.
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Combining common genetic variants and non-genetic risk factors to predict risk of cutaneous melanoma. Hum Mol Genet. 2018 12 01; 27(23):4145-4156.
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Transancestral mapping and genetic load in systemic lupus erythematosus. Nat Commun. 2017 07 17; 8:16021.
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Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry. Genes Immun. 2017 03; 18(2):88-94.
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Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting. Circulation. 2017 May 30; 135(22):2091-2101.
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Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease. N Engl J Med. 2016 12 15; 375(24):2349-2358.