Tissue Inhibitor of Metalloproteinase-1
"Tissue Inhibitor of Metalloproteinase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a N-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumor invasion in vitro.
| Descriptor ID |
D019715
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| MeSH Number(s) |
D12.776.645.875.450
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Tissue Inhibitor of Metalloproteinase-1".
Below are MeSH descriptors whose meaning is more specific than "Tissue Inhibitor of Metalloproteinase-1".
This graph shows the total number of publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in this website by year, and whether "Tissue Inhibitor of Metalloproteinase-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Tissue Inhibitor of Metalloproteinase-1" by people in Profiles.
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The Development of Translational Biomarkers as a Tool for Improving the Understanding, Diagnosis and Treatment of Chronic Neuropathic Pain. Mol Neurobiol. 2018 03; 55(3):2420-2430.
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Tissue Inhibitor of Metalloproteinase-1: Actions beyond Matrix Metalloproteinase Inhibition. Cardiology. 2015; 132(3):147-50.
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Activation of the Wnt/ß-catenin pathway and tissue inhibitor of metalloprotease 1 during tertiary dentinogenesis. J Biochem. 2013 Jan; 153(1):43-50.
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TGF-beta suppresses the upregulation of MMP-2 by vascular smooth muscle cells in response to PDGF-BB. Am J Physiol Cell Physiol. 2010 Jan; 298(1):C191-201.
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Interleukin-6 (IL-6) modulates migration and matrix metalloproteinase function in dermal fibroblasts from IL-6KO mice. Br J Dermatol. 2007 Jun; 156(6):1163-71.
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Involvement of inflammation, degradation, and apoptosis in a mouse model of glaucoma. J Biol Chem. 2005 Sep 02; 280(35):31240-8.
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Selenium's effects on MMP-2 and TIMP-1 secretion by human trabecular meshwork cells. Invest Ophthalmol Vis Sci. 2004 Feb; 45(2):473-9.
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Differential expression of matrix metalloproteinases and their tissue-derived inhibitors in cutaneous wound repair. Plast Reconstr Surg. 2000 Feb; 105(2):638-47.
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Activation of gelatinase-tissue-inhibitors-of-metalloproteinase complexes by matrilysin. Biochem J. 1998 May 01; 331 ( Pt 3):965-72.