"Receptor, Adenosine A1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of tissues including the BRAIN and DORSAL HORN NEURONS. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.
| Descriptor ID |
D043682
|
| MeSH Number(s) |
D12.776.543.750.695.700.700.100 D12.776.543.750.720.700.700.100
|
| Concept/Terms |
Receptor, Adenosine A1- Receptor, Adenosine A1
- Adenosine A1 Receptors
- Receptors, Adenosine A1
- Adenosine A1 Receptor
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Adenosine A1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P1 [D12.776.543.750.695.700.700]
- Receptor, Adenosine A1 [D12.776.543.750.695.700.700.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P1 [D12.776.543.750.720.700.700]
- Receptor, Adenosine A1 [D12.776.543.750.720.700.700.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Adenosine A1".
This graph shows the total number of publications written about "Receptor, Adenosine A1" by people in this website by year, and whether "Receptor, Adenosine A1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Receptor, Adenosine A1" by people in Profiles.
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IL-11 is required for A1 adenosine receptor-mediated protection against ischemic AKI. J Am Soc Nephrol. 2013 Oct; 24(10):1558-70.
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A1 adenosine receptor allosteric enhancer PD-81723 protects against renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 2012 Sep; 303(5):F721-32.
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Proximal tubule sphingosine kinase-1 has a critical role in A1 adenosine receptor-mediated renal protection from ischemia. Kidney Int. 2012 Oct; 82(8):878-91.
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Protection against acute kidney injury via A(1) adenosine receptor-mediated Akt activation reduces liver injury after liver ischemia and reperfusion in mice. J Pharmacol Exp Ther. 2010 Jun; 333(3):736-47.