"Glycogen Phosphorylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes the degradation of GLYCOGEN in animals by releasing glucose-1-phosphate from the terminal alpha-1,4-glycosidic bond. This enzyme exists in two forms: an active phosphorylated form ( PHOSPHORYLASE A) and an inactive un-phosphorylated form (PHOSPHORYLASE B). Both a and b forms of phosphorylase exist as homodimers. In mammals, the major isozymes of glycogen phosphorylase are found in muscle, liver and brain tissue.
| Descriptor ID |
D024981
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| MeSH Number(s) |
D08.811.913.400.450.460.400.186
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Phosphorylase".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Phosphorylase".
This graph shows the total number of publications written about "Glycogen Phosphorylase" by people in this website by year, and whether "Glycogen Phosphorylase" was a major or minor topic of these publications.
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Below are the most recent publications written about "Glycogen Phosphorylase" by people in Profiles.
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Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase. Proteins. 2005 Dec 01; 61(4):966-83.
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New approach to pharmacophore mapping and QSAR analysis using inductive logic programming. Application to thermolysin inhibitors and glycogen phosphorylase B inhibitors. J Med Chem. 2002 Jan 17; 45(2):399-409.