"Protein Denaturation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.
| Descriptor ID |
D011489
|
| MeSH Number(s) |
E05.793.500 G01.154.651.750.500 G02.111.688.750.500
|
| Concept/Terms |
Protein Denaturation- Protein Denaturation
- Denaturation, Protein
- Denaturations, Protein
- Protein Denaturations
|
Below are MeSH descriptors whose meaning is more general than "Protein Denaturation".
Below are MeSH descriptors whose meaning is more specific than "Protein Denaturation".
This graph shows the total number of publications written about "Protein Denaturation" by people in this website by year, and whether "Protein Denaturation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1996 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 3 | 3 |
| 2012 | 0 | 3 | 3 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 2 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Denaturation" by people in Profiles.
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Droplet-Based Microfluidic Temperature-Jump Platform for the Rapid Assessment of Biomolecular Kinetics. Anal Chem. 2022 Dec 06; 94(48):16675-16684.
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Best practices and benchmarks for intact protein analysis for top-down mass spectrometry. Nat Methods. 2019 07; 16(7):587-594.
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Protein Extraction from Gels: A Brief Review. Methods Mol Biol. 2019; 1855:479-482.
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Defining Gas-Phase Fragmentation Propensities of Intact Proteins During Native Top-Down Mass Spectrometry. J Am Soc Mass Spectrom. 2017 06; 28(6):1203-1215.
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Mapping Proteoforms and Protein Complexes From King Cobra Venom Using Both Denaturing and Native Top-down Proteomics. Mol Cell Proteomics. 2016 07; 15(7):2423-34.
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Fluorescence study of domain structure and lipid interaction of human apolipoproteins E3 and E4. Biochim Biophys Acta. 2014 Dec; 1841(12):1716-24.
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Overproduction and biophysical characterization of human HSP70 proteins. Protein Expr Purif. 2015 Feb; 106:57-65.
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Development of a high-throughput screening cancer cell-based luciferase refolding assay for identifying Hsp90 inhibitors. Assay Drug Dev Technol. 2013 Oct; 11(8):478-88.
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Fluorescence analysis of the lipid binding-induced conformational change of apolipoprotein E4. Biochemistry. 2012 Jul 17; 51(28):5580-8.
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Hyaluronan synthase mediates dye translocation across liposomal membranes. BMC Biochem. 2012 Jan 25; 13:2.