"HMGA1a Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An 11-kDa AT-hook motif-containing (AT-HOOK MOTIFS) protein that binds to the minor grove of AT-rich regions of DNA. It is the full-length product of the alternatively-spliced HMGA1 gene and may function as an architectural chromatin binding protein that is involved in transcriptional regulation.
| Descriptor ID |
D025741
|
| MeSH Number(s) |
D12.776.260.312.500 D12.776.660.235.400.500.100 D12.776.664.235.400.500.100
|
| Concept/Terms |
HMGA1a Protein- HMGA1a Protein
- High Mobility Group I(Y) Protein
- HMGI(Y) Gene Product
- HMG I-Y Phosphoprotein
- HMG I Y Phosphoprotein
- Phosphoprotein, HMG I-Y
- HMG-I(Y) Protein
- HMGI Protein
- AT-Hook 1a Protein, High Mobility Group
- AT Hook 1a Protein, High Mobility Group
- HMG I-Type Protein
- HMG I Type Protein
|
Below are MeSH descriptors whose meaning is more general than "HMGA1a Protein".
Below are MeSH descriptors whose meaning is more specific than "HMGA1a Protein".
This graph shows the total number of publications written about "HMGA1a Protein" by people in this website by year, and whether "HMGA1a Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "HMGA1a Protein" by people in Profiles.
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HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression. Blood. 2022 05 05; 139(18):2797-2815.
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IL-24 modulates the high mobility group (HMG) A1/miR222 /AKT signaling in lung cancer cells. Oncotarget. 2016 Oct 25; 7(43):70247-70263.
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Microarray analysis reveals that high mobility group A1 is involved in colorectal cancer metastasis. Oncol Rep. 2013 Sep; 30(3):1488-96.