"Serum Response Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A MADS domain-containing transcription factor that binds to the SERUM RESPONSE ELEMENT in the promoter-enhancer region of many genes. It is one of the four founder proteins that structurally define the superfamily of MADS DOMAIN PROTEINS.
| Descriptor ID |
D026362
|
| MeSH Number(s) |
D12.776.260.400.249.875 D12.776.930.397.875
|
| Concept/Terms |
Serum Response Factor- Serum Response Factor
- Response Factor, Serum
- Transcription Factor SRF
- c-fos Serum Response Factor
- c fos Serum Response Factor
|
Below are MeSH descriptors whose meaning is more general than "Serum Response Factor".
Below are MeSH descriptors whose meaning is more specific than "Serum Response Factor".
This graph shows the total number of publications written about "Serum Response Factor" by people in this website by year, and whether "Serum Response Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Serum Response Factor" by people in Profiles.
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BRG1 (Brahma-Related Gene 1) Promotes Endothelial Mrtf Transcription to Establish Embryonic Capillary Integrity. Arterioscler Thromb Vasc Biol. 2017 09; 37(9):1674-1682.
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Early growth response protein-1 mediates lipotoxicity-associated placental inflammation: role in maternal obesity. Am J Physiol Endocrinol Metab. 2013 Jul 01; 305(1):E1-14.
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Regulation of alpha-smooth muscle actin expression in granulation tissue myofibroblasts is dependent on the intronic CArG element and the transforming growth factor-beta1 control element. Am J Pathol. 2005 May; 166(5):1343-51.
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Signalling pathways: jack of all cascades. Curr Biol. 1996 Jan 01; 6(1):16-9.
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Signal integration at the c-fos promoter. Carcinogenesis. 1995 Mar; 16(3):443-50.
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Transcriptional repression mediated by the serum response factor. FEBS Lett. 1995 Jan 02; 357(1):45-9.
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Co-occurrence of CArG boxes and TCF sites within viral genomes. Biochem Biophys Res Commun. 1994 Nov 30; 205(1):545-51.
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C-terminal phosphorylation of the serum-response factor. Eur J Biochem. 1993 Sep 01; 216(2):469-75.
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Elk-1 protein domains required for direct and SRF-assisted DNA-binding. Nucleic Acids Res. 1992 Jul 11; 20(13):3317-24.
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Identification of multiple SRF N-terminal phosphorylation sites affecting DNA binding properties. EMBO J. 1992 Mar; 11(3):1045-54.