"Sphingolipids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of membrane lipids that have a polar head and two nonpolar tails. They are composed of one molecule of the long-chain amino alcohol sphingosine (4-sphingenine) or one of its derivatives, one molecule of a long-chain acid, a polar head alcohol and sometimes phosphoric acid in diester linkage at the polar head group. (Lehninger et al, Principles of Biochemistry, 2nd ed)
| Descriptor ID |
D013107
|
| MeSH Number(s) |
D10.570.877
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sphingolipids".
Below are MeSH descriptors whose meaning is more specific than "Sphingolipids".
This graph shows the total number of publications written about "Sphingolipids" by people in this website by year, and whether "Sphingolipids" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 2 | 3 |
| 2019 | 0 | 1 | 1 |
| 2022 | 0 | 2 | 2 |
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Below are the most recent publications written about "Sphingolipids" by people in Profiles.
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Ablation of Sphingosine Kinase 1 Protects Cornea from Neovascularization in a Mouse Corneal Injury Model. Cells. 2022 09 17; 11(18).
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Lipidomic profiling in the Strong Heart Study identified American Indians at risk of chronic kidney disease. Kidney Int. 2022 Nov; 102(5):1154-1166.
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Global Metabolomic Profiling Reveals Disrupted Lipid and Amino Acid Metabolism Between the Acute and Chronic Stages of Ischemic Stroke. J Stroke Cerebrovasc Dis. 2022 Apr; 31(4):106320.
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Sphingosine Kinase-1 Is Essential for Maintaining External/Outer Limiting Membrane and Associated Adherens Junctions in the Aging Retina. Mol Neurobiol. 2019 Oct; 56(10):7188-7207.
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Metabolic Profiles of Obesity in American Indians: The Strong Heart Family Study. PLoS One. 2016; 11(7):e0159548.
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Sphingolipid profile alters in retinal dystrophic P23H-1 rats and systemic FTY720 can delay retinal degeneration. J Lipid Res. 2016 05; 57(5):818-31.
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Role of Acid Sphingomyelinase in Shifting the Balance Between Proinflammatory and Reparative Bone Marrow Cells in Diabetic Retinopathy. Stem Cells. 2016 Apr; 34(4):972-83.
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Sphingolipids in ocular inflammation. Adv Exp Med Biol. 2014; 801:623-9.
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Retinal sphingolipids and their very-long-chain fatty acid-containing species. Invest Ophthalmol Vis Sci. 2010 Sep; 51(9):4422-31.
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Determination of cellular lipids bound to human CD1d molecules. PLoS One. 2009; 4(5):e5325.