Header Logo

Connection

Doris Benbrook to Structure-Activity Relationship

This is a "connection" page, showing publications Doris Benbrook has written about Structure-Activity Relationship.
  1. Tetrahydroquinoline units in flexible heteroarotinoids (Flex-Hets) convey anti-cancer properties in A2780 ovarian cancer cells. Bioorg Med Chem. 2020 01 01; 28(1):115244.
    View in: PubMed
    Score: 0.162
  2. Development of flexible-heteroarotinoids for kidney cancer. Mol Cancer Ther. 2009 May; 8(5):1227-38.
    View in: PubMed
    Score: 0.078
  3. Synthesis of flexible sulfur-containing heteroarotinoids that induce apoptosis and reactive oxygen species with discrimination between malignant and benign cells. J Med Chem. 2004 Feb 12; 47(4):999-1007.
    View in: PubMed
    Score: 0.054
  4. Novel heteroarotinoids as potential antagonists of Mycobacterium bovis BCG. J Med Chem. 2004 Feb 12; 47(4):1008-17.
    View in: PubMed
    Score: 0.054
  5. Refining retinoids with heteroatoms. Mini Rev Med Chem. 2002 Jun; 2(3):277-83.
    View in: PubMed
    Score: 0.048
  6. Heteroarotinoids inhibit head and neck cancer cell lines in vitro and in vivo through both RAR and RXR retinoic acid receptors. J Med Chem. 1999 Oct 21; 42(21):4434-45.
    View in: PubMed
    Score: 0.040
  7. Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids. J Med Chem. 1999 Sep 09; 42(18):3602-14.
    View in: PubMed
    Score: 0.040
  8. Synthesis and biological evaluation of SHetA2 (NSC-721689) analogs against the ovarian cancer cell line A2780. Eur J Med Chem. 2019 May 15; 170:16-27.
    View in: PubMed
    Score: 0.039
  9. Synthesis and characterization of heteroarotinoids demonstrate structure specificity relationships. J Med Chem. 1998 Sep 10; 41(19):3753-7.
    View in: PubMed
    Score: 0.037
  10. Synthesis and evaluation of second generation Flex-Het scaffolds against the human ovarian cancer A2780 cell line. Eur J Med Chem. 2015; 96:209-17.
    View in: PubMed
    Score: 0.029
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.