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Jeanie Tryggestad

TitleProf,Asoc
InstitutionUniversity of Oklahoma Health Sciences Center
DepartmentDept of Pediatrics
AddressOUCPB 4500
1200 Children's Ave
Oklahoma City OK 73104
Phone405/271-6764 ext 43080
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    R03DK125626     (TRYGGESTAD, JEANIE BEATRICE)Apr 1, 2021 - Mar 31, 2023
    NIH
    Impact of in utero diabetes exposure on miRNA: effects on cellular metabolism
    Role: Principal Investigator

    K23DK106533     (TRYGGESTAD, JEANIE BEATRICE)Sep 12, 2016 - Sep 30, 2021
    NIH
    In utero exposure to diabetes and future cardiometabolic risk: the role of miRNA
    Role: Principal Investigator

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    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shah KB, Fields DA, Pezant NP, Kharoud HK, Gulati S, Jacobs K, Gale CA, Kharbanda EO, Nagel EM, Demerath EW, Tryggestad JB. Corrigendum to: "Gestational Diabetes Mellitus Is Associated with Altered Abundance of Exosomal MicroRNAs in Human Milk" [Clin Therapeut 44(2) (2022) 172-185]. Clin Ther. 2022 Jul; 44(7):1034. PMID: 35595570.
      Citations:    Fields:    
    2. Landreth S, Teague AM, Jensen ME, Gulati S, Tryggestad JB. Impact of maternal diabetes exposure on soluble adhesion molecules in the offspring. Nutr Metab Cardiovasc Dis. 2022 05; 32(5):1253-1258. PMID: 35256229.
      Citations:    Fields:    Translation:HumansCells
    3. Shah AS, Gidding SS, El Ghormli L, Tryggestad JB, Nadeau KJ, Bacha F, Levitt Katz LE, Willi SM, Lima J, Urbina EM. Relationship between Arterial Stiffness and Subsequent Cardiac Structure and Function in Young Adults with Youth-Onset Type 2 Diabetes: Results from the TODAY Study. J Am Soc Echocardiogr. 2022 06; 35(6):620-628.e4. PMID: 35149207.
      Citations: 5     Fields:    Translation:Humans
    4. Shah KB, Fields DA, Pezant NP, Kharoud HK, Gulati S, Jacobs K, Gale CA, Kharbanda EO, Nagel EM, Demerath EW, Tryggestad JB. Gestational Diabetes Mellitus Is Associated with Altered Abundance of Exosomal MicroRNAs in Human Milk. Clin Ther. 2022 02; 44(2):172-185.e1. PMID: 35090750.
      Citations: 13     Fields:    Translation:HumansCells
    5. Pincu Y, Tryggestad JB, Teague AM, Short KR. The effect of a high fat meal on heart rate variability and arterial stiffness in adolescents with or without type 1 diabetes. J Diabetes Complications. 2022 03; 36(3):108130. PMID: 35067450.
      Citations:    Fields:    Translation:Humans
    6. Shah RD, Braffett BH, Tryggestad JB, Hughan KS, Dhaliwal R, Nadeau KJ, Levitt Katz LE, Gidding SS. Cardiovascular risk factor progression in adolescents and young adults with youth-onset type 2 diabetes. J Diabetes Complications. 2022 03; 36(3):108123. PMID: 35123868.
      Citations: 4     Fields:    Translation:Humans
    7. Shah AS, El Ghormli L, Gidding SS, Hughan KS, Levitt Katz LE, Koren D, Tryggestad JB, Bacha F, Braffett BH, Arslanian S, Urbina EM. Longitudinal changes in vascular stiffness and heart rate variability among young adults with youth-onset type 2 diabetes: results from the follow-up observational treatment options for type 2 diabetes in adolescents and youth (TODAY) study. Acta Diabetol. 2022 Feb; 59(2):197-205. PMID: 34542729.
      Citations: 7     Fields:    Translation:Humans
    8. Todd JN, Kleinberger JW, Zhang H, Srinivasan S, Tollefsen SE, Levitsky LL, Levitt Katz LE, Tryggestad JB, Bacha F, Imperatore G, Lawrence JM, Pihoker C, Divers J, Flannick J, Dabelea D, Florez JC, Pollin TI. Monogenic Diabetes in Youth With Presumed Type 2 Diabetes: Results From the Progress in Diabetes Genetics in Youth (ProDiGY) Collaboration. Diabetes Care. 2021 Aug 06. PMID: 34362814.
      Citations: 7     Fields:    
    9. Bjornstad P, Drews KL, Caprio S, Gubitosi-Klug R, Nathan DM, Tesfaldet B, Tryggestad J, White NH, Zeitler P. Long-Term Complications in Youth-Onset Type 2 Diabetes. N Engl J Med. 2021 07 29; 385(5):416-426. PMID: 34320286.
      Citations: 101     Fields:    Translation:Humans
    10. Rughani A, Friedman JE, Tryggestad JB. Type 2 Diabetes in Youth: the Role of Early Life Exposures. Curr Diab Rep. 2020 08 07; 20(9):45. PMID: 32767148.
      Citations: 14     Fields:    Translation:Humans
    11. Rughani A, Blick K, Pang H, Marin M, Meyer J, Tryggestad JB. Pseudohypertriglyceridemia: A Novel Case with Important Clinical Implications. Case Rep Pediatr. 2020; 2020:4609317. PMID: 32832184.
      Citations: 1     
    12. Jiang S, Teague AM, Tryggestad JB, Lyons TJ, Chernausek SD. Fetal circulating human resistin increases in diabetes during pregnancy and impairs placental mitochondrial biogenesis. Mol Med. 2020 08 06; 26(1):76. PMID: 32762639.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    13. Shah KB, Chernausek SD, Teague AM, Bard DE, Tryggestad JB. Maternal diabetes alters microRNA expression in fetal exosomes, human umbilical vein endothelial cells and placenta. Pediatr Res. 2021 04; 89(5):1157-1163. PMID: 32663836.
      Citations: 16     Fields:    Translation:HumansCells
    14. Tryggestad JB, Shah RD, Braffett BH, Bacha F, Gidding SS, Gubitosi-Klug RA, Shah AS, Urbina EM, Levitt Katz LE. Circulating adhesion molecules and associations with HbA1c, hypertension, nephropathy, and retinopathy in the Treatment Options for type 2 Diabetes in Adolescent and Youth study. Pediatr Diabetes. 2020 09; 21(6):923-931. PMID: 32501612.
      Citations: 8     Fields:    Translation:Humans
    15. Jiang S, Teague AM, Tryggestad JB, Jensen ME, Chernausek SD. Role of metformin in epigenetic regulation of placental mitochondrial biogenesis in maternal diabetes. Sci Rep. 2020 05 20; 10(1):8314. PMID: 32433500.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    16. Tryggestad JB, Chernausek SD. BMI changes through childhood: the impact on puberty, linear growth and hormonal regulation. Pediatr Res. 2020 07; 88(1):11-13. PMID: 32299087.
      Citations: 1     Fields:    Translation:Humans
    17. Ansell SKD, Jester M, Tryggestad JB, Short KR. A pilot study of the effects of a high-intensity aerobic exercise session on heart rate variability and arterial compliance in adolescents with or without type 1 diabetes. Pediatr Diabetes. 2020 05; 21(3):486-495. PMID: 31951305.
      Citations: 3     Fields:    Translation:Humans
    18. Tryggestad JB, Teague AM, Sparling DP, Jiang S, Chernausek SD. Macrophage-Derived microRNA-155 Increases in Obesity and Influences Adipocyte Metabolism by Targeting Peroxisome Proliferator-Activated Receptor Gamma. Obesity (Silver Spring). 2019 11; 27(11):1856-1864. PMID: 31531958.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    19. Shah AS, El Ghormli L, Vajravelu ME, Bacha F, Farrell RM, Gidding SS, Levitt Katz LE, Tryggestad JB, White NH, Urbina EM. Heart Rate Variability and Cardiac Autonomic Dysfunction: Prevalence, Risk Factors, and Relationship to Arterial Stiffness in the Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study. Diabetes Care. 2019 11; 42(11):2143-2150. PMID: 31501226.
      Citations: 32     Fields:    Translation:Humans
    20. Chadwick JQ, Copeland KC, Branam DE, Erb-Alvarez JA, Khan SI, Peercy MT, Rogers ME, Saunkeah BR, Tryggestad JB, Wharton DF. Genomic Research and American Indian Tribal Communities in Oklahoma: Learning From Past Research Misconduct and Building Future Trusting Partnerships. Am J Epidemiol. 2019 07 01; 188(7):1206-1212. PMID: 31081852.
      Citations: 10     Fields:    Translation:Humans
    21. Arslanian S, El Ghormli L, Young Kim J, Bacha F, Chan C, Ismail HM, Levitt Katz LE, Levitsky L, Tryggestad JB, White NH. The Shape of the Glucose Response Curve During an Oral Glucose Tolerance Test: Forerunner of Heightened Glycemic Failure Rates and Accelerated Decline in ß-Cell Function in TODAY. Diabetes Care. 2019 01; 42(1):164-172. PMID: 30455329.
      Citations: 23     Fields:    Translation:HumansCells
    22. Slover RH, Tryggestad JB, DiMeglio LA, Fox LA, Bode BW, Bailey TS, Brazg R, Christiansen MP, Sherr JL, Tsalikian E, Kaiserman KB, Sullivan A, Huang S, Shin J, Lee SW, Kaufman FR. Accuracy of a Fourth-Generation Continuous Glucose Monitoring System in Children and Adolescents with Type 1 Diabetes. Diabetes Technol Ther. 2018 09; 20(9):576-584. PMID: 30063162.
      Citations: 13     Fields:    Translation:Humans
    23. Shah AS, El Ghormli L, Gidding SS, Bacha F, Nadeau KJ, Levitt Katz LE, Tryggestad JB, Leibel N, Hale DE, Urbina EM. Prevalence of arterial stiffness in adolescents with type 2 diabetes in the TODAY cohort: Relationships to glycemic control and other risk factors. J Diabetes Complications. 2018 Aug; 32(8):740-745. PMID: 29936086.
      Citations: 16     Fields:    Translation:Humans
    24. Venditti EM, Tan K, Chang N, Laffel L, McGinley G, Miranda N, Tryggestad JB, Walders-Abramson N, Yasuda P, Delahanty L. Barriers and strategies for oral medication adherence among children and adolescents with Type 2 diabetes. Diabetes Res Clin Pract. 2018 May; 139:24-31. PMID: 29427697.
      Citations: 10     Fields:    Translation:Humans
    25. Gidding SS, Bacha F, Bjornstad P, Levitt Katz LE, Levitsky LL, Lynch J, Tryggestad JB, Weinstock RS, El Ghormli L, Lima JAC. Cardiac Biomarkers in Youth with Type 2 Diabetes Mellitus: Results from the TODAY Study. J Pediatr. 2018 01; 192:86-92.e5. PMID: 29246363.
      Citations: 5     Fields:    Translation:Humans
    26. Jiang S, Teague AM, Tryggestad JB, Aston CE, Lyons T, Chernausek SD. Effects of maternal diabetes and fetal sex on human placenta mitochondrial biogenesis. Placenta. 2017 Sep; 57:26-32. PMID: 28864016.
      Citations: 20     Fields:    Translation:Humans
    27. Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM, Lin AE, Katsanis N, Jones PL, Crowley WF, Davis EE, FitzPatrick DR, Talkowski ME. Corrigendum: SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 05 26; 49(6):969. PMID: 28546579.
      Citations:    Fields:    
    28. Jiang S, Teague AM, Tryggestad JB, Chernausek SD. Role of microRNA-130b in placental PGC-1a/TFAM mitochondrial biogenesis pathway. Biochem Biophys Res Commun. 2017 06 03; 487(3):607-612. PMID: 28433632.
      Citations: 23     Fields:    Translation:HumansCells
    29. Shaw ND, Brand H, Kupchinsky ZA, Bengani H, Plummer L, Jones TI, Erdin S, Williamson KA, Rainger J, Stortchevoi A, Samocha K, Currall BB, Dunican DS, Collins RL, Willer JR, Lek A, Lek M, Nassan M, Pereira S, Kammin T, Lucente D, Silva A, Seabra CM, Chiang C, An Y, Ansari M, Rainger JK, Joss S, Smith JC, Lippincott MF, Singh SS, Patel N, Jing JW, Law JR, Ferraro N, Verloes A, Rauch A, Steindl K, Zweier M, Scheer I, Sato D, Okamoto N, Jacobsen C, Tryggestad J, Chernausek S, Schimmenti LA, Brasseur B, Cesaretti C, García-Ortiz JE, Buitrago TP, Silva OP, Hoffman JD, Mühlbauer W, Ruprecht KW, Loeys BL, Shino M, Kaindl AM, Cho CH, Morton CC, Meehan RR, van Heyningen V, Liao EC, Balasubramanian R, Hall JE, Seminara SB, Macarthur D, Moore SA, Yoshiura KI, Gusella JF, Marsh JA, Graham JM, Lin AE, Katsanis N, Jones PL, Crowley WF, Davis EE, FitzPatrick DR, Talkowski ME. SMCHD1 mutations associated with a rare muscular dystrophy can also cause isolated arhinia and Bosma arhinia microphthalmia syndrome. Nat Genet. 2017 Feb; 49(2):238-248. PMID: 28067909.
      Citations: 74     Fields:    Translation:Humans
    30. Tryggestad JB, Vishwanath A, Jiang S, Mallappa A, Teague AM, Takahashi Y, Thompson DM, Chernausek SD. Influence of gestational diabetes mellitus on human umbilical vein endothelial cell miRNA. Clin Sci (Lond). 2016 11 01; 130(21):1955-67. PMID: 27562513.
      Citations: 31     Fields:    Translation:HumansCells
    31. Walders-Abramson N, Anderson B, Larkin ME, Chang N, Venditti E, Bzdick S, Tryggestad JB, Tan K, Geffner ME, Hirst K. Benefits and barriers to participating in longitudinal research of youth-onset type 2 diabetes: Results from the TODAY retention survey. Clin Trials. 2016 Apr; 13(2):240-3. PMID: 26531295.
      Citations: 6     Fields:    Translation:Humans
    32. Marin MT, Dasari PS, Tryggestad JB, Aston CE, Teague AM, Short KR. Oxidized HDL and LDL in adolescents with type 2 diabetes compared to normal weight and obese peers. J Diabetes Complications. 2015 Jul; 29(5):679-85. PMID: 25881918.
      Citations: 15     Fields:    Translation:HumansCells
    33. Tryggestad JB, Willi SM. Complications and comorbidities of T2DM in adolescents: findings from the TODAY clinical trial. J Diabetes Complications. 2015 Mar; 29(2):307-12. PMID: 25468310.
      Citations: 29     Fields:    Translation:Humans
    34. Tryggestad JB, Wang JJ, Zhang SX, Thompson DM, Short KR. Elevated plasma pigment epithelium-derived factor in children with type 2 diabetes mellitus is attributable to obesity. Pediatr Diabetes. 2015 Dec; 16(8):600-5. PMID: 25293868.
      Citations: 6     Fields:    Translation:Humans
    35. Tryggestad JB, Short KR. Arterial compliance in obese children: implications for cardiovascular health. Exerc Sport Sci Rev. 2014 Oct; 42(4):175-82. PMID: 25062003.
      Citations: 5     Fields:    Translation:Humans
    36. Tryggestad JB, Thompson DM, Copeland KC, Short KR. Arterial compliance is increased in children with type 2 diabetes compared with normal weight peers but not obese peers. Pediatr Diabetes. 2013 Jun; 14(4):259-66. PMID: 23458165.
      Citations: 8     Fields:    Translation:Humans
    37. Tryggestad JB, Li S, Chernausek SD. Hypogonadotropic hypogonadism presenting with arhinia: a case report. J Med Case Rep. 2013 Feb 22; 7:52. PMID: 23432817.
      Citations: 3     Fields:    
    38. Blackett P, Tryggestad J, Krishnan S, Li S, Xu W, Alaupovic P, Quiroga C, Copeland K. Lipoprotein abnormalities in compound heterozygous lipoprotein lipase deficiency after treatment with a low-fat diet and orlistat. J Clin Lipidol. 2013 Mar-Apr; 7(2):132-9. PMID: 23415432.
      Citations: 6     Fields:    Translation:Humans
    39. Sunderland KL, Tryggestad JB, Wang JJ, Teague AM, Pratt LV, Zhang SX, Thompson DM, Short KR. Pigment epithelium-derived factor (PEDF) varies with body composition and insulin resistance in healthy young people. J Clin Endocrinol Metab. 2012 Nov; 97(11):E2114-8. PMID: 22930782.
      Citations: 7     Fields:    Translation:Humans
    40. Tryggestad JB, Thompson DM, Copeland KC, Short KR. Sex differences in vascular compliance in normal-weight but not obese boys and girls: the effect of body composition. Int J Pediatr. 2012; 2012:607895. PMID: 22505944.
      Citations: 5     
    41. Palmer BW, Wisniewski AB, Schaeffer TL, Mallappa A, Tryggestad JB, Krishnan S, Chalmers LJ, Copeland K, Chernausek SD, Reiner WG, Kropp BP. A model of delivering multi-disciplinary care to people with 46 XY DSD. J Pediatr Urol. 2012 Feb; 8(1):7-16. PMID: 22078657.
      Citations: 16     Fields:    Translation:Humans
    42. Tryggestad JB, Thompson DM, Copeland KC, Short KR. Obese children have higher arterial elasticity without a difference in endothelial function: the role of body composition. Obesity (Silver Spring). 2012 Jan; 20(1):165-71. PMID: 21996664.
      Citations: 32     Fields:    Translation:Humans
    43. Schaeffer TL, Tryggestad JB, Mallappa A, Hanna AE, Krishnan S, Chernausek SD, Chalmers LJ, Reiner WG, Kropp BP, Wisniewski AB. An Evidence-Based Model of Multidisciplinary Care for Patients and Families Affected by Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency. Int J Pediatr Endocrinol. 2010; 2010:692439. PMID: 20339513.
      Citations: 7     
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