Paul Cook to Structure-Activity Relationship
This is a "connection" page, showing publications Paul Cook has written about Structure-Activity Relationship.
Connection Strength
0.334
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Alpha,beta-elimination reaction of O-acetylserine sulfhydrylase. Is the pyridine ring required? Biochim Biophys Acta. 2003 Apr 11; 1647(1-2):66-9.
Score: 0.052
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Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound. J Mol Biol. 2000 Oct 20; 303(2):279-86.
Score: 0.044
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Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry. J Mol Biol. 1998; 283(1):135-46.
Score: 0.036
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Role of the divalent metal ion in the NAD:malic enzyme reaction: an ESEEM determination of the ground state conformation of malate in the E:Mn:malate complex. Protein Sci. 1996 Aug; 5(8):1648-54.
Score: 0.033
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The 2'-phosphate of NADP is critical for optimum productive binding to 6-phosphogluconate dehydrogenase from Candida utilis. Arch Biochem Biophys. 1993 Sep; 305(2):551-8.
Score: 0.027
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Chemical mechanism of 6-phosphogluconate dehydrogenase from Candida utilis from pH studies. Biochemistry. 1993 Mar 02; 32(8):2041-6.
Score: 0.026
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Divergent effects of compounds on the hydrolysis and transpeptidation reactions of ?-glutamyl transpeptidase. J Enzyme Inhib Med Chem. 2012 Aug; 27(4):476-89.
Score: 0.023
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Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature. J Med Chem. 2010 Jan 14; 53(1):345-56.
Score: 0.021
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A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase. J Biol Chem. 2009 Apr 03; 284(14):9059-65.
Score: 0.019
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Kinetic studies on the activation of pyrophosphate-dependent phosphofructokinase from mung bean by fructose 2,6-bisphosphate and related compounds. Biochemistry. 1986 Aug 12; 25(16):4682-7.
Score: 0.016
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Surface-exposed tryptophan residues are essential for O-acetylserine sulfhydrylase structure, function, and stability. J Biol Chem. 2003 Sep 26; 278(39):37511-9.
Score: 0.013
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Secondary deuterium and nitrogen-15 isotope effects in enzyme-catalyzed reactions. Chemical mechanism of liver alcohol dehydrogenase. Biochemistry. 1981 Mar 31; 20(7):1817-25.
Score: 0.011
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Overall mechanism and rate equation for O-acetylserine sulfhydrylase. J Biol Chem. 1977 May 25; 252(10):3459.
Score: 0.009
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Effector-induced conformational transitions in Ascaris suum phosphofructokinase. A fluorescence and circular dichroism study. J Biol Chem. 1991 May 15; 266(14):8884-90.
Score: 0.006