Topoisomerase I Inhibitors
                             
                            
                            
                                
                            
                            
                                
                            
                            
                            
                                
                                    
                                            
	"Topoisomerase I Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				Compounds that inhibit the activity of DNA TOPOISOMERASE I.
    
			
			
				
				
					
						| Descriptor ID | D059004 | 
					
						| MeSH Number(s) | D27.505.519.389.892.500 D27.505.954.248.794.500 | 
					
						| Concept/Terms | Topoisomerase I InhibitorsTopoisomerase I InhibitorsInhibitors, Topoisomerase ITopoisomerase 1 InhibitorsInhibitors, Topoisomerase 1DNA Topoisomerase I InhibitorsDNA Type 1 Topoisomerase Inhibitors
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				Below are MeSH descriptors whose meaning is more general than "Topoisomerase I Inhibitors".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Topoisomerase I Inhibitors".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Topoisomerase I Inhibitors" by people in this website by year, and whether "Topoisomerase I Inhibitors" was a major or minor topic of these publications. 
				
					 
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		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 2010 | 1 | 0 | 1 | 
| 2017 | 0 | 1 | 1 | 
| 2019 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "Topoisomerase I Inhibitors" by people in Profiles.
						
					
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								Anticancer Drug Affects Metabolomic Profiles in Multicellular Spheroids: Studies Using Mass Spectrometry Imaging Combined with Machine Learning. Anal Chem. 2019 05 07; 91(9):5802-5809. 
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								Microscale Mass Spectrometry Analysis of Extracellular Metabolites in Live Multicellular Tumor Spheroids. Anal Chem. 2017 09 05; 89(17):9069-9076. 
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								A phase II study of two topotecan regimens evaluated in recurrent platinum-sensitive ovarian, fallopian tube or primary peritoneal cancer: a Gynecologic Oncology Group Study (GOG 146Q). Gynecol Oncol. 2011 Mar; 120(3):454-8.