Role of antioxidant and detoxification defense mechanisms in e-cigarettes induced oxidative stress
Biography
Overview
Specific aims of this project are: (1) to investigate if e-cigs impair Nrf2 regulation of antioxidant, detoxification, and inflammatory responses in the lung cells; and (2) to determine whether sulforaphane (SFN) can reverse e-cig induced oxidative stress and inflammation in mouse lungs.
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