Pulmonary Surfactant-Associated Protein D
"Pulmonary Surfactant-Associated Protein D" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens and enhances their opsinization and killing by phagocytic cells. Surfactant protein D contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.
| Descriptor ID |
D037663
|
| MeSH Number(s) |
D12.776.503.280.249.625 D12.776.823.249
|
| Concept/Terms |
Pulmonary Surfactant-Associated Protein D- Pulmonary Surfactant-Associated Protein D
- Pulmonary Surfactant Associated Protein D
- Lung Protein D
- Surfactant-Associated Glycoprotein D
- Surfactant Associated Glycoprotein D
- Surfactant Protein D
- SP-D
- Pulmonary Surfactant Protein D
|
Below are MeSH descriptors whose meaning is more general than "Pulmonary Surfactant-Associated Protein D".
Below are MeSH descriptors whose meaning is more specific than "Pulmonary Surfactant-Associated Protein D".
This graph shows the total number of publications written about "Pulmonary Surfactant-Associated Protein D" by people in this website by year, and whether "Pulmonary Surfactant-Associated Protein D" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Pulmonary Surfactant-Associated Protein D" by people in Profiles.
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Effects of SPA4 peptide on lipopolysaccharide-disrupted lung epithelial barrier, injury, and function in a human cell system and mouse model of lung injury. Physiol Rep. 2022 07; 10(13):e15353.
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Retinal degeneration mutation in Sftpa1tm1Kor/J and Sftpd -/- targeted mice. PLoS One. 2018; 13(7):e0199824.
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Structure, genetics and function of the pulmonary associated surfactant proteins A and D: The extra-pulmonary role of these C type lectins. Ann Anat. 2017 May; 211:184-201.
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Intra-amniotic LPS and antenatal betamethasone: inflammation and maturation in preterm lamb lungs. Am J Physiol Lung Cell Mol Physiol. 2012 Feb 15; 302(4):L380-9.
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Surfactant protein (SP)-A and SP-D as antimicrobial and immunotherapeutic agents. Recent Pat Antiinfect Drug Discov. 2010 Jun; 5(2):115-23.
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Coccidioides posadasii infection alters the expression of pulmonary surfactant proteins (SP)-A and SP-D. Respir Res. 2004 Dec 10; 5:28.
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Deficiencies in lung surfactant proteins A and D are associated with lung infection in very premature neonatal baboons. Am J Respir Crit Care Med. 2001 Feb; 163(2):389-97.
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Surfactant proteins A and D in premature baboons with chronic lung injury (Bronchopulmonary dysplasia). Evidence for an inhibition of secretion. Am J Respir Crit Care Med. 1999 Sep; 160(3):942-9.