"Dextran Sulfate" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Long-chain polymer of glucose containing 17-20% sulfur. It has been used as an anticoagulant and also has been shown to inhibit the binding of HIV-1 to CD4-POSITIVE T-LYMPHOCYTES. It is commonly used as both an experimental and clinical laboratory reagent and has been investigated for use as an antiviral agent, in the treatment of hypolipidemia, and for the prevention of free radical damage, among other applications.
| Descriptor ID |
D016264
|
| MeSH Number(s) |
D09.698.365.272.300
|
| Concept/Terms |
Dextran Sulfate Sodium- Dextran Sulfate Sodium
- Sulfate Sodium, Dextran
- Sodium Dextran Sulfate
- Dextran Sulfate, Sodium
- Sulfate, Sodium Dextran
|
Below are MeSH descriptors whose meaning is more general than "Dextran Sulfate".
Below are MeSH descriptors whose meaning is more specific than "Dextran Sulfate".
This graph shows the total number of publications written about "Dextran Sulfate" by people in this website by year, and whether "Dextran Sulfate" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Dextran Sulfate" by people in Profiles.
-
Inhibition of MK2 suppresses IL-1ß, IL-6, and TNF-a-dependent colorectal cancer growth. Int J Cancer. 2018 04 15; 142(8):1702-1711.
-
Ablation of Doublecortin-Like Kinase 1 in the Colonic Epithelium Exacerbates Dextran Sulfate Sodium-Induced Colitis. PLoS One. 2015; 10(8):e0134212.
-
Toll-like receptor-7 ligand Imiquimod induces type I interferon and antimicrobial peptides to ameliorate dextran sodium sulfate-induced acute colitis. Inflamm Bowel Dis. 2012 May; 18(5):955-67.
-
Granulocyte macrophage colony-stimulating factor ameliorates DSS-induced experimental colitis. Inflamm Bowel Dis. 2008 Jan; 14(1):88-99.
-
Cross-organ sensitization of lumbosacral spinal neurons receiving urinary bladder input in rats with inflamed colon. Gastroenterology. 2005 Dec; 129(6):1967-78.
-
Colonic inflammation increases Na+ currents in bladder sensory neurons. Neuroreport. 2004 Dec 03; 15(17):2601-5.