"Clonal Anergy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Functional inactivation of T- or B-lymphocytes rendering them incapable of eliciting an immune response to antigen. This occurs through different mechanisms in the two kinds of lymphocytes and can contribute to SELF TOLERANCE.
| Descriptor ID |
D017635
|
| MeSH Number(s) |
G12.535.425.100
|
| Concept/Terms |
Clonal Anergy- Clonal Anergy
- Anergies, Clonal
- Anergy, Clonal
- Clonal Anergies
|
Below are MeSH descriptors whose meaning is more general than "Clonal Anergy".
Below are MeSH descriptors whose meaning is more specific than "Clonal Anergy".
This graph shows the total number of publications written about "Clonal Anergy" by people in this website by year, and whether "Clonal Anergy" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clonal Anergy" by people in Profiles.
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Single Cell Transcriptomics Implicate Novel Monocyte and T Cell Immune Dysregulation in Sarcoidosis. Front Immunol. 2020; 11:567342.
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CD5-dependent CK2 activation pathway regulates threshold for T cell anergy. J Immunol. 2012 Sep 15; 189(6):2918-30.
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Histone deacetylase inhibitor uses p21(Cip1) to maintain anergy in CD4+ T cells. Int Immunopharmacol. 2009 Oct; 9(11):1289-97.
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Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. J Exp Med. 2009 Jan 16; 206(1):139-51.
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Histone deacetylase inhibitors induce antigen specific anergy in lymphocytes: a comparative study. Int Immunopharmacol. 2006 Nov; 6(11):1673-81.
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Transcriptional modulation of TCR, Notch and Wnt signaling pathways in SEB-anergized CD4+ T cells. Genes Immun. 2005 Oct; 6(7):596-608.