"Integrin alpha1beta1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Integrin alpha1beta1 functions as a receptor for LAMININ and COLLAGEN. It is widely expressed during development, but in the adult is the predominant laminin receptor (RECEPTORS, LAMININ) in mature SMOOTH MUSCLE CELLS, where it is important for maintenance of the differentiated phenotype of these cells. Integrin alpha1beta1 is also found in LYMPHOCYTES and microvascular endothelial cells, and may play a role in angiogenesis. In SCHWANN CELLS and neural crest cells, it is involved in cell migration. Integrin alpha1beta1 is also known as VLA-1 and CD49a-CD29.
| Descriptor ID |
D039222
|
| MeSH Number(s) |
D12.776.543.750.685.100 D12.776.543.750.705.408.850.099 D12.776.543.750.705.876.249
|
| Concept/Terms |
Integrin alpha1beta1- Integrin alpha1beta1
- alpha1beta1, Integrin
- VLA-1
- Integrin alpha(1)beta(1)
- CD49a-CD29
- alpha1beta1 Integrin
- Integrin, alpha1beta1
|
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