"Caspase 9" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A long pro-domain caspase that contains a CASPASE RECRUITMENT DOMAIN in its pro-domain region. Caspase 9 is activated during cell stress by mitochondria-derived proapoptotic factors and by CARD SIGNALING ADAPTOR PROTEINS such as APOPTOTIC PROTEASE-ACTIVATING FACTOR 1. It activates APOPTOSIS by cleaving and activating EFFECTOR CASPASES.
| Descriptor ID |
D053453
|
| MeSH Number(s) |
D08.811.277.656.262.500.126.550.900 D08.811.277.656.300.200.126.550.900 D12.644.360.024.131.155 D12.644.360.075.358.155 D12.644.360.075.405.550.900 D12.776.157.057.006.155 D12.776.476.024.139.155 D12.776.476.075.358.155 D12.776.476.075.405.550.900
|
| Concept/Terms |
Caspase 9- Caspase 9
- ICE-Like Apoptotic Protease 6
- ICE Like Apoptotic Protease 6
- Apoptotic Protease Activating Factor 3
- ICE-LAP6 Protein
- ICE LAP6 Protein
- Caspase-9
Procaspase-9- Procaspase-9
- Procaspase 9
- Pro-Caspase-9
- Pro Caspase 9
|
Below are MeSH descriptors whose meaning is more general than "Caspase 9".
Below are MeSH descriptors whose meaning is more specific than "Caspase 9".
This graph shows the total number of publications written about "Caspase 9" by people in this website by year, and whether "Caspase 9" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Caspase 9" by people in Profiles.
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Quercetin inhibits human metastatic ovarian cancer cell growth and modulates components of the intrinsic apoptotic pathway in PA-1?cell line. Chem Biol Interact. 2019 Feb 25; 300:91-100.
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Nanosomes carrying doxorubicin exhibit potent anticancer activity against human lung cancer cells. Sci Rep. 2016 12 12; 6:38541.
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Tumor-targeted and pH-controlled delivery of doxorubicin using gold nanorods for lung cancer therapy. Int J Nanomedicine. 2015; 10:6773-88.
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Curcumin sensitizes human lung cancer cells to apoptosis and metastasis synergistically combined with carboplatin. Exp Biol Med (Maywood). 2015 Nov; 240(11):1416-25.
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CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1235-44.
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Induction of apoptosis in human cancer cell lines by diospyrin, a plant-derived bisnaphthoquinonoid, and its synthetic derivatives. Cancer Lett. 2002 Dec 15; 188(1-2):85-93.
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MBP-1 mediated apoptosis involves cytochrome c release from mitochondria. Oncogene. 2002 Apr 25; 21(18):2775-84.
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Interferon-gamma-induced apoptotic responses of Fanconi anemia group C hematopoietic progenitor cells involve caspase 8-dependent activation of caspase 3 family members. Blood. 2000 Dec 15; 96(13):4204-11.