Small Leucine-Rich Proteoglycans
"Small Leucine-Rich Proteoglycans" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A proteoglycan family (SLRPs) that is defined by a central domain which consists of a variable number of repeats of the motif LXXLxLXXNxL, where L may be LEUCINE; ISOLEUCINE; VALINE; or other hydrophobic amino acids. The N-terminal contains four conserved CYSTEINE residues and may be modified depending on function. SLRPs provide structural support to the EXTRACELLULAR MATRIX and are critical for regulating its assembly and dynamics at CELL-MATRIX JUNCTIONS.
| Descriptor ID |
D000071232
|
| MeSH Number(s) |
D09.698.735.700 D12.776.395.650.875 D12.776.860.300.806
|
| Concept/Terms |
Small Leucine-Rich Proteoglycans- Small Leucine-Rich Proteoglycans
- Small Leucine Rich Proteoglycans
- SLRP Proteoglycans
- Small Leucine-Rich Repeat Proteoglycans
- Small Leucine Rich Repeat Proteoglycans
- Small Leucine-Rich Repeat Proteoglycan
- Small Leucine Rich Repeat Proteoglycan
|
Below are MeSH descriptors whose meaning is more general than "Small Leucine-Rich Proteoglycans".
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