1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
"1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
| Descriptor ID |
D019307
|
| MeSH Number(s) |
D02.886.590.700.545 D03.383.606.527 D03.633.100.531.400
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine".
Below are MeSH descriptors whose meaning is more specific than "1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine".
This graph shows the total number of publications written about "1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine" by people in this website by year, and whether "1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
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Below are the most recent publications written about "1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine" by people in Profiles.
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Efficacy and safety of fasudil in patients with stable angina: a double-blind, placebo-controlled, phase 2 trial. J Am Coll Cardiol. 2005 Nov 15; 46(10):1803-11.
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Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase. Exp Cell Res. 2000 Feb 01; 254(2):210-20.
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Effect of protein kinase C activators on the phosphorylation and the surface expression of the CDw50 leukocyte antigen. Eur J Biochem. 1992 Jan 15; 203(1-2):321-6.