Microsatellite Instability
"Microsatellite Instability" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The occurrence of highly polymorphic mono- and dinucleotide MICROSATELLITE REPEATS in somatic cells. It is a form of genome instability associated with defects in DNA MISMATCH REPAIR.
| Descriptor ID |
D053842
|
| MeSH Number(s) |
C23.550.362.590 G05.365.590.335.590 G05.370.590
|
| Concept/Terms |
Replication Error Phenotype- Replication Error Phenotype
- Error Phenotype, Replication
- Error Phenotypes, Replication
- Phenotype, Replication Error
- Phenotypes, Replication Error
- Replication Error Phenotypes
|
Below are MeSH descriptors whose meaning is more general than "Microsatellite Instability".
Below are MeSH descriptors whose meaning is more specific than "Microsatellite Instability".
This graph shows the total number of publications written about "Microsatellite Instability" by people in this website by year, and whether "Microsatellite Instability" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 2 | 1 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Microsatellite Instability" by people in Profiles.
-
Characterization of KRAS Mutation Subtypes in Non-small Cell Lung Cancer. Mol Cancer Ther. 2021 12; 20(12):2577-2584.
-
Large-scale analysis of KMT2 mutations defines a distinctive molecular subset with treatment implication in gastric cancer. Oncogene. 2021 07; 40(30):4894-4905.
-
Population bias in somatic measurement of microsatellite instability status. Cancer Med. 2020 09; 9(17):6452-6460.
-
An Emerging Landscape for Canonical and Actionable Molecular Alterations in Primary and Metastatic Prostate Cancer. Mol Cancer Ther. 2020 06; 19(6):1373-1382.
-
Comparison of the biomarkers for targeted therapies in primary extra-mammary and mammary Paget's disease. Cancer Med. 2020 02; 9(4):1441-1450.
-
Relationship between protein biomarkers of chemotherapy response and microsatellite status, tumor mutational burden and PD-L1 expression in cancer patients. Int J Cancer. 2020 06 01; 146(11):3087-3097.
-
Comprehensive genomic profiling of recurrent endometrial cancer: Implications for selection of systemic therapy. Gynecol Oncol. 2019 09; 154(3):461-466.
-
Theranostic molecular profiling of pleomorphic ductal carcinoma of the breast. Breast J. 2019 01; 25(1):175-176.
-
Comprehensive analysis of cancers of unknown primary for the biomarkers of response to immune checkpoint blockade therapy. Eur J Cancer. 2018 05; 94:179-186.
-
Microsatellite instability status determined by next-generation sequencing and compared with PD-L1 and tumor mutational burden in 11,348 patients. Cancer Med. 2018 03; 7(3):746-756.