"DNA Fragmentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Splitting the DNA into shorter pieces by endonucleolytic DNA CLEAVAGE at multiple sites. It includes the internucleosomal DNA fragmentation, which along with chromatin condensation, are considered to be the hallmarks of APOPTOSIS.
Descriptor ID |
D053938
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MeSH Number(s) |
G05.200.230
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "DNA Fragmentation".
Below are MeSH descriptors whose meaning is more specific than "DNA Fragmentation".
This graph shows the total number of publications written about "DNA Fragmentation" by people in this website by year, and whether "DNA Fragmentation" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 2 | 2 |
2005 | 0 | 1 | 1 |
2006 | 0 | 4 | 4 |
2007 | 0 | 2 | 2 |
2008 | 0 | 1 | 1 |
2012 | 0 | 1 | 1 |
2014 | 1 | 1 | 2 |
2015 | 0 | 1 | 1 |
2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA Fragmentation" by people in Profiles.
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Synergistic therapy with tangeretin and 5-fluorouracil accelerates the ROS/JNK mediated apoptotic pathway in human colorectal cancer cell. Food Chem Toxicol. 2020 Sep; 143:111529.
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Quercetin inhibits human metastatic ovarian cancer cell growth and modulates components of the intrinsic apoptotic pathway in PA-1?cell line. Chem Biol Interact. 2019 Feb 25; 300:91-100.
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A novel component from citrus, ginger, and mushroom family exhibits antitumor activity on human meningioma cells through suppressing the Wnt/ß-catenin signaling pathway. Tumour Biol. 2015 Sep; 36(9):7027-34.
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Post mortem DNA degradation of human tissue experimentally mummified in salt. PLoS One. 2014; 9(10):e110753.
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Acquired tumor cell radiation resistance at the treatment site is mediated through radiation-orchestrated intercellular communication. Int J Radiat Oncol Biol Phys. 2014 Mar 01; 88(3):677-85.
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NDRG4, the N-Myc downstream regulated gene, is important for cell survival, tumor invasion and angiogenesis in meningiomas. Integr Biol (Camb). 2012 Oct; 4(10):1185-97.
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Role of BCL-XL in photoreceptor survival. Adv Exp Med Biol. 2008; 613:69-74.
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Alteration of apoptotic signaling molecules as a function of time after radiation in human neuroblastoma cells. Mol Cell Biochem. 2008 Mar; 310(1-2):167-79.
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Furosemide prevents apoptosis and associated gene expression in a rat model of surgical ischemic acute renal failure. Ren Fail. 2007; 29(4):399-407.
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Loss of BCL-XL in rod photoreceptors: Increased susceptibility to bright light stress. Invest Ophthalmol Vis Sci. 2006 Dec; 47(12):5583-9.