HIV Reverse Transcriptase
"HIV Reverse Transcriptase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A reverse transcriptase encoded by the POL GENE of HIV. It is a heterodimer of 66 kDa and 51 kDa subunits that are derived from a common precursor protein. The heterodimer also includes an RNAse H activity (RIBONUCLEASE H, HUMAN IMMUNODEFICIENCY VIRUS) that plays an essential role the viral replication process.
| Descriptor ID |
D054303
|
| MeSH Number(s) |
D08.811.913.696.445.308.300.750.187 D12.776.964.775.375.545.875 D12.776.964.775.375.750.187 D12.776.964.775.562.764.875 D12.776.964.970.600.850.375.545.875 D12.776.964.970.600.850.375.750.187
|
| Concept/Terms |
HIV Reverse Transcriptase- HIV Reverse Transcriptase
- Transcriptase, HIV Reverse
- Reverse Transcriptase, Human Immunodeficiency Virus
- Reverse Transcriptase, HIV
|
Below are MeSH descriptors whose meaning is more general than "HIV Reverse Transcriptase".
Below are MeSH descriptors whose meaning is more specific than "HIV Reverse Transcriptase".
This graph shows the total number of publications written about "HIV Reverse Transcriptase" by people in this website by year, and whether "HIV Reverse Transcriptase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "HIV Reverse Transcriptase" by people in Profiles.
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Synthesis, biological evaluation and molecular modeling studies of new 2,3-diheteroaryl thiazolidin-4-ones as NNRTIs. Chem Biol Drug Des. 2015 Nov; 86(5):1285-91.
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Emergence of HIV-1 variants containing codon insertions and deletions in the beta3-beta4 hairpin loop domain of reverse transcriptase. Immunol Lett. 2000 Oct 03; 74(2):173-5.