"Filamins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of crosslinking filament proteins encoded by distinct FLN genes. Filamins are involved in cell adhesion, spreading, and migration, acting as scaffolds for over 90 binding partners including channels, receptors, intracellular signaling molecules and transcription factors. Due to the range of molecular interactions, mutations in FLN genes result in anomalies with moderate to lethal consequences.
Descriptor ID |
D064448
|
MeSH Number(s) |
A11.284.430.214.190.750.050.414 D05.750.078.730.315 D12.776.210.249 D12.776.220.525.315
|
Concept/Terms |
Filamin B- Filamin B
- beta-Filamin
- beta Filamin
- beta-Filamins
- Filamin 1-Like Protein
- 1-Like Protein, Filamin
- 1-Like Proteins, Filamin
- Filamin 1 Like Protein
- Filamin 1-Like Proteins
- Protein, Filamin 1-Like
- Proteins, Filamin 1-Like
Filamin A- Filamin A
- Filamin 1
- alpha-Filamin
- alpha Filamin
- alpha-Filamins
- 280 kDa Actin-Binding Protein
- 280 kDa Actin Binding Protein
|
Below are MeSH descriptors whose meaning is more general than "Filamins".
Below are MeSH descriptors whose meaning is more specific than "Filamins".
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