A protein deglycase that repairs methylglyoxal- and glyoxal-glycated amino acids and proteins, releasing repaired proteins and lactate or glycolate. It deglycates CYSTEINE, ARGININE and LYSINE residues to reactivate proteins by reversing glycation and prevent the formation of ADVANCED GLYCATION END PRODUCTS. It protects cells against OXIDATIVE STRESS and CELL DEATH by functioning as an oxidative stress sensor and redox-sensitive MOLECULAR CHAPERONE and PROTEASE. Mutations in the PARK7 gene are associated with autosomal-recessive, early-onset PARKINSON DISEASE.

Descriptor ID	D000071617
MeSH Number(s)	D08.811.277.785 D12.776.637.875
Concept/Terms	Protein Deglycase DJ-1 Protein Deglycase DJ-1 DJ-1, Protein Deglycase DJ-1-PARK7 Protein DJ 1 PARK7 Protein DJ-1 Protein DJ 1 Protein Parkinson Protein 7 DJ1 Protein PARK7 Protein Parkinsonism Associated Deglycase Deglycase, Parkinsonism Associated

Below are MeSH descriptors whose meaning is more general than "Protein Deglycase DJ-1".

Below are MeSH descriptors whose meaning is related to "Protein Deglycase DJ-1".

Below are MeSH descriptors whose meaning is more specific than "Protein Deglycase DJ-1".