Matrix Attachment Regions
"Matrix Attachment Regions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Regions of the CHROMATIN or DNA that bind to the NUCLEAR MATRIX. They are found in INTERGENIC DNA, especially flanking the 5' ends of genes or clusters of genes. Many of the regions that have been isolated contain a bipartite sequence motif called the MAR/SAR recognition signature sequence that binds to MATRIX ATTACHMENT REGION BINDING PROTEINS.
| Descriptor ID |
D045170
|
| MeSH Number(s) |
G02.111.570.080.534 G05.360.080.534
|
| Concept/Terms |
Matrix Attachment Regions- Matrix Attachment Regions
- Matrix Attachment Region
- Region, Matrix Attachment
- Regions, Matrix Attachment
- Scaffold-Attached Regions
- Region, Scaffold-Attached
- Regions, Scaffold-Attached
- Scaffold Attached Regions
- Scaffold-Attached Region
- SAR Elements
- Element, SAR
- Elements, SAR
- SAR Element
- Scaffold Attachment Regions
- Region, Scaffold Attachment
- Regions, Scaffold Attachment
- Scaffold Attachment Region
- MAR Elements
- Element, MAR
- Elements, MAR
- MAR Element
- Matrix-Attached Regions
- Matrix Attached Regions
- Matrix-Attached Region
- Region, Matrix-Attached
- Regions, Matrix-Attached
MRS Sequence- MRS Sequence
- MRS Sequences
- Sequences, MRS
- MAR-SAR Recognition Signature Sequence
- MAR SAR Recognition Signature Sequence
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Below are MeSH descriptors whose meaning is more general than "Matrix Attachment Regions".
Below are MeSH descriptors whose meaning is more specific than "Matrix Attachment Regions".
This graph shows the total number of publications written about "Matrix Attachment Regions" by people in this website by year, and whether "Matrix Attachment Regions" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "Matrix Attachment Regions" by people in Profiles.
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Episomal maintenance of S/MAR-containing non-viral vectors for RPE-based diseases. Adv Exp Med Biol. 2014; 801:703-9.
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S/MAR-containing DNA nanoparticles promote persistent RPE gene expression and improvement in RPE65-associated LCA. Hum Mol Genet. 2013 Apr 15; 22(8):1632-42.