"VDJ Recombinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Recombinases involved in the rearrangement of immunity-related GENES such as IMMUNOGLOBULIN GENES and T-CELL RECEPTOR GENES.
| Descriptor ID |
D045567
|
| MeSH Number(s) |
D08.811.739.900 D08.811.913.696.445.950
|
| Concept/Terms |
VDJ Recombinases- VDJ Recombinases
- V-(D)-J Recombinase
- VDJ Recombinase
- Recombinase, VDJ
- V(D)J Recombinase
- V-D-J Recombinase
- Recombinase, V-D-J
- V D J Recombinase
Immunoglobulin Recombinases- Immunoglobulin Recombinases
- Recombinases, Immunoglobulin
- Immunoglobulin Recombinase
- Recombinase, Immunoglobulin
|
Below are MeSH descriptors whose meaning is more general than "VDJ Recombinases".
Below are MeSH descriptors whose meaning is more specific than "VDJ Recombinases".
This graph shows the total number of publications written about "VDJ Recombinases" by people in this website by year, and whether "VDJ Recombinases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "VDJ Recombinases" by people in Profiles.
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Riches in RAGs: Revealing the V(D)J Recombinase through High-Resolution Structures. Trends Biochem Sci. 2017 01; 42(1):72-84.
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An interdomain boundary in RAG1 facilitates cooperative binding to RAG2 in formation of the V(D)J recombinase complex. Protein Sci. 2015 May; 24(5):861-73.
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Spatio-temporal regulation of RAG2 following genotoxic stress. DNA Repair (Amst). 2015 Mar; 27:19-27.
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A non-sequence-specific DNA binding mode of RAG1 is inhibited by RAG2. J Mol Biol. 2009 Apr 03; 387(3):744-58.
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Thermal dependency of RAG1 self-association properties. BMC Biochem. 2008 Jan 30; 9:5.
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DNA cleavage of a cryptic recombination signal sequence by RAG1 and RAG2. Implications for partial V(H) gene replacement. J Biol Chem. 2006 May 05; 281(18):12370-80.
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DNA cleavage activity of the V(D)J recombination protein RAG1 is autoregulated. Mol Cell Biol. 2004 Aug; 24(15):6850-60.
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Self-association and conformational properties of RAG1: implications for formation of the V(D)J recombinase. Nucleic Acids Res. 2003 Apr 01; 31(7):2014-23.
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The central domain of core RAG1 preferentially recognizes single-stranded recombination signal sequence heptamer. J Biol Chem. 2003 May 16; 278(20):18235-40.
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Identification of two topologically independent domains in RAG1 and their role in macromolecular interactions relevant to V(D)J recombination. J Biol Chem. 2001 Oct 05; 276(40):37093-101.