"Laron Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5.
| Descriptor ID |
D046150
|
| MeSH Number(s) |
C05.116.099.343.679 C16.320.240.750 C19.297.656
|
| Concept/Terms |
Laron Syndrome- Laron Syndrome
- Syndrome, Laron
- Growth Hormone Receptor Defect
- Growth Hormone Receptor Deficiency
- Pituitary Dwarfism II
- Dwarfism II, Pituitary
- Dwarfism IIs, Pituitary
- Pituitary Dwarfism IIs
- Laron Type Dwarfism I
- Primary GH Resistance
- GH Resistance, Primary
- Primary Growth Hormone Resistance
- Severe GH Insensitivity
- Growth Hormone Insensitivity Syndrome
- Laron Dwarfism
- Dwarfism, Laron
|
Below are MeSH descriptors whose meaning is more general than "Laron Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Laron Syndrome".
This graph shows the total number of publications written about "Laron Syndrome" by people in this website by year, and whether "Laron Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Laron Syndrome" by people in Profiles.
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The insulin-like growth factors and growth disorders of childhood. Endocrinol Metab Clin North Am. 2012 Jun; 41(2):265-82, v.
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The emerging role of IGF-1 deficiency in cardiovascular aging: recent advances. J Gerontol A Biol Sci Med Sci. 2012 Jun; 67(6):599-610.
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Long-term treatment with recombinant insulin-like growth factor (IGF)-I in children with severe IGF-I deficiency due to growth hormone insensitivity. J Clin Endocrinol Metab. 2007 Mar; 92(3):902-10.