"Smad7 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inhibitory smad protein that associates with TRANSFORMING GROWTH FACTOR BETA RECEPTORS and BONE MORPHOGENETIC PROTEIN RECEPTORS. It negatively regulates SIGNAL TRANSDUCTION PATHWAYS by inhibiting PHOSPHORYLATION of RECEPTOR-REGULATED SMAD PROTEINS.
| Descriptor ID |
D051906
|
| MeSH Number(s) |
D12.644.360.024.334.200.700 D12.776.157.057.170.249.700 D12.776.476.024.428.249.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Smad7 Protein".
Below are MeSH descriptors whose meaning is more specific than "Smad7 Protein".
This graph shows the total number of publications written about "Smad7 Protein" by people in this website by year, and whether "Smad7 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Smad7 Protein" by people in Profiles.
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Transforming growth factor-ß and psoriasis: a new link. Br J Dermatol. 2017 12; 177(6):1480-1481.
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Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer. Gynecol Oncol. 2005 Feb; 96(2):368-73.
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HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81. J Biol Chem. 2003 Nov 07; 278(45):44377-84.
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TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses. Oncogene. 2002 Aug 22; 21(37):5783-90.
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Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue. J Biol Chem. 2002 Aug 23; 277(34):30754-9.
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Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene. J Cell Biochem. 2002; 87(2):233-41.