An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression.

An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression. PLoS Genet. 2013; 9(9):e1003750.

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subject areas

Alleles
DNA-Binding Proteins
Enhancer Elements, Genetic
Gene Expression Regulation
Genetic Predisposition to Disease
Haplotypes
HEK293 Cells
Humans
Intracellular Signaling Peptides and Proteins
Lupus Erythematosus, Systemic
Matrix Attachment Region Binding Proteins
NF-kappa B
Nuclear Proteins
Polymorphism, Single Nucleotide
Promoter Regions, Genetic
Signal Transduction
Tumor Necrosis Factor alpha-Induced Protein 3

authors with profiles

Patrick Gaffney