Positive Regulatory Domain I-Binding Factor 1
"Positive Regulatory Domain I-Binding Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional repressor protein that contains an N-terminal PR-SET domain, four C-terminal CYS2-HIS2 ZINC FINGERS, and binds the PRDI element in the INTERFERON-BETA gene. It has methyltransferase activity and mediates gene transcription in tissue-specific innate and adaptive immune lymphocyte T-CELLS, repressing expression of proteins that promote exit of these tissue-specific T-cell populations from non-lymphoid organs.
| Descriptor ID |
D000074462
|
| MeSH Number(s) |
D08.811.913.555.500.800.700 D12.776.260.703.650 D12.776.930.780.904
|
| Concept/Terms |
Positive Regulatory Domain I-Binding Factor 1- Positive Regulatory Domain I-Binding Factor 1
- Positive Regulatory Domain I Binding Factor 1
- PRDI-BF1 Protein
- PRDI BF1 Protein
- B Lymphocyte-Induced Maturation Protein 1
- B Lymphocyte Induced Maturation Protein 1
- PRDM1 Protein
- BLIMP1 Protein
|
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