"CELF Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of RRM proteins which contain two N-terminal RNA RECOGNITION MOTIF (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 amino acids between the second and third RRM domains. They regulate pre-mRNA ALTERNATIVE SPLICING and also function in RNA EDITING and PROTEIN BIOSYNTHESIS.
| Descriptor ID |
D000067878
|
| MeSH Number(s) |
D12.776.157.725.813.250 D12.776.664.962.813.250
|
| Concept/Terms |
CELF Proteins- CELF Proteins
- Proteins, CELF
- BRUNOL Proteins
- Proteins, BRUNOL
- CUGBP, Elav-Like Family Member Proteins
- CUGBP, Elav Like Family Member Proteins
- CUG Triplet Repeat, RNA-Binding Proteins
- CUG Triplet Repeat, RNA Binding Proteins
- CUG-BP Proteins
- CUG BP Proteins
- Proteins, CUG-BP
- CUGBP Proteins
- Proteins, CUGBP
- Bruno-Like Family Member Proteins
- Bruno Like Family Member Proteins
|
Below are MeSH descriptors whose meaning is more general than "CELF Proteins".
Below are MeSH descriptors whose meaning is more specific than "CELF Proteins".
This graph shows the total number of publications written about "CELF Proteins" by people in this website by year, and whether "CELF Proteins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 0 | 3 | 3 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "CELF Proteins" by people in Profiles.
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RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells. PLoS One. 2011 Feb 11; 6(2):e16958.
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CUGBP2 downregulation by prostaglandin E2 protects colon cancer cells from radiation-induced mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol. 2008 May; 294(5):G1235-44.
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Translation inhibition during cell cycle arrest and apoptosis: Mcl-1 is a novel target for RNA binding protein CUGBP2. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G1025-32.
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Novel intestinal splice variants of RNA-binding protein CUGBP2: isoform-specific effects on mitotic catastrophe. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G971-81.
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Functional antagonism between RNA binding proteins HuR and CUGBP2 determines the fate of COX-2 mRNA translation. Gastroenterology. 2007 Mar; 132(3):1055-65.
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Dynamic antagonism between RNA-binding protein CUGBP2 and cyclooxygenase-2-mediated prostaglandin E2 in radiation damage. Proc Natl Acad Sci U S A. 2004 Sep 21; 101(38):13873-8.
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CUGBP2 plays a critical role in apoptosis of breast cancer cells in response to genotoxic injury. Ann N Y Acad Sci. 2003 Dec; 1010:504-9.
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Coupled mRNA stabilization and translational silencing of cyclooxygenase-2 by a novel RNA binding protein, CUGBP2. Mol Cell. 2003 Jan; 11(1):113-26.