"ADAM10 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disintegrin and metalloproteinase domain-containing protein. It cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA between ALANINE 76 and VALINE 77 to its functional form, as well as several other CELL SURFACE PROTEINS to their soluble forms, including AMYLOID BETA-PROTEIN PRECURSOR and PRION PROTEIN.
| Descriptor ID |
D000072197
|
| MeSH Number(s) |
D08.811.277.656.675.374.102.250 D09.400.430.500.250 D12.776.395.033.250
|
| Concept/Terms |
ADAM10 Protein- ADAM10 Protein
- CD156w Antigen
- Antigen, CD156w
- CD156c Antigen
- Antigen, CD156c
- Disintegrin and Metalloproteinase Domain-Containing Protein 10
- Disintegrin and Metalloproteinase Domain Containing Protein 10
- ADAM-10 Protein
- ADAM 10 Protein
|
Below are MeSH descriptors whose meaning is more general than "ADAM10 Protein".
Below are MeSH descriptors whose meaning is more specific than "ADAM10 Protein".
This graph shows the total number of publications written about "ADAM10 Protein" by people in this website by year, and whether "ADAM10 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "ADAM10 Protein" by people in Profiles.
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Heightened cleavage of Axl receptor tyrosine kinase by ADAM metalloproteases may contribute to disease pathogenesis in SLE. Clin Immunol. 2016 08; 169:58-68.