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Bestrophins

"Bestrophins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A protein family characterized by a highly conserved N-terminus and four to six transmembrane helices; they function as bicarbonate permeable, calcium-activated chloride channels. Bestrophin-1 (BEST-1) and bestrophin-2 are highly expressed in human RETINAL PIGMENT EPITHELIUM cells and mutations in the BEST-1 gene are associated with VITELLIFORM MACULAR DYSTROPHY, TYPE 2.


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This graph shows the total number of publications written about "Bestrophins" by people in this website by year, and whether "Bestrophins" was a major or minor topic of these publications.
Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2008 and 2009 and 2010 and 2013 and 2021
To see the data from this visualization as text, click here.