"Anesthetics, Local" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Drugs that block nerve conduction when applied locally to nerve tissue in appropriate concentrations. They act on any part of the nervous system and on every type of nerve fiber. In contact with a nerve trunk, these anesthetics can cause both sensory and motor paralysis in the innervated area. Their action is completely reversible. (From Gilman AG, et. al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed) Nearly all local anesthetics act by reducing the tendency of voltage-dependent sodium channels to activate.
| Descriptor ID |
D000779
|
| MeSH Number(s) |
D27.505.696.277.100.200 D27.505.696.663.850.025 D27.505.954.427.210.100.200
|
| Concept/Terms |
Anesthetics, Local- Anesthetics, Local
- Local Anesthetics
- Conduction-Blocking Anesthetics
- Conduction Blocking Anesthetics
- Anesthetics, Conduction-Blocking
- Anesthetics, Conduction Blocking
|
Below are MeSH descriptors whose meaning is more general than "Anesthetics, Local".
Below are MeSH descriptors whose meaning is more specific than "Anesthetics, Local".
This graph shows the total number of publications written about "Anesthetics, Local" by people in this website by year, and whether "Anesthetics, Local" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2001 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Anesthetics, Local" by people in Profiles.
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EFFECTIVENESS OF PHENTOLAMINE MESYLATE IN REVERSAL OF LOCAL ANESTHESIA: SYSTEMATIC REVIEW AND META-ANALYSIS. J Evid Based Dent Pract. 2023 09; 23(3):101861.
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A multicenter study to evaluate the pharmacokinetics and safety of liposomal bupivacaine for postsurgical analgesia in pediatric patients aged 6 to less than 17 years (PLAY). J Clin Anesth. 2021 12; 75:110503.
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Incidence of Epinephrine Reactions With Local Anesthesia in Mohs Micrographic Surgery. Dermatol Surg. 2020 05; 46(5):581-585.
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Safety of Intradermal/Subcutaneous Lidocaine With Epinephrine Use in Dermatologic Surgery. Dermatol Surg. 2020 01; 46(1):26-30.
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Laparoscopic-guided abdominal wall nerve blocks in the pediatric population: a novel technique with comparison to ultrasound-guided blocks and local wound infiltration alone. Surgery. 2018 03; 163(3):622-626.
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Development of a novel technique for bilateral rectus sheath nerve blocks under laparoscopic-guidance. J Pediatr Surg. 2017 Jun; 52(6):966-969.
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A case series of peripheral nerve blocks in pediatrics and young adults with skeletal dysplasia. Paediatr Anaesth. 2016 May; 26(5):553-6.
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Randomized clinical trial of subcutaneous versus interfascial bupivacaine for pain control after midline laparotomy. Br J Surg. 2013 May; 100(6):743-8.
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Percutaneous adhesiolysis in the management of chronic low back pain in post lumbar surgery syndrome and spinal stenosis: a systematic review. Pain Physician. 2012 Jul-Aug; 15(4):E435-62.
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Poison control therapy. Am J Nurs. 2009 Dec; 109(12):42-5.