"PHD Zinc Fingers" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Zinc finger domains of approximately 50 to 80 amino acids in length that are characterized by a conserved Cysteine(3)-Histidine-Cysteine(4) amino acid motif which coordinates binding of two zinc ions. They are similar structurally to RING FINGER DOMAINS, with a globular fold topology of two BETA-SHEETS and an ALPHA-HELIX. PHD fingers occur in many proteins that function in chromatin-mediated gene expression and EPIGENETICS such as POLYCOMB-GROUP PROTEINS.
| Descriptor ID |
D000075925
|
| MeSH Number(s) |
G02.111.570.820.709.275.500.985.438
|
| Concept/Terms |
PHD Zinc Fingers- PHD Zinc Fingers
- Finger, PHD Zinc
- Fingers, PHD Zinc
- Zinc Finger, PHD
- Zinc Fingers, PHD
- PHD Fingers
- Finger, PHD
- Fingers, PHD
- PHD Finger
- PHD Motifs
- PHD Domains
- Domain, PHD
- Domains, PHD
- PHD Domain
- PHD Zinc Finger
- PHD Finger Domain
- Domain, PHD Finger
- Domains, PHD Finger
- Finger Domain, PHD
- Finger Domains, PHD
- PHD Finger Domains
- PHD Motif
- Motif, PHD
- Motifs, PHD
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Below are MeSH descriptors whose meaning is more general than "PHD Zinc Fingers".
Below are MeSH descriptors whose meaning is more specific than "PHD Zinc Fingers".
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