Antidepressive Agents, Tricyclic
"Antidepressive Agents, Tricyclic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that contain a fused three-ring moiety and are used in the treatment of depression. These drugs block the uptake of norepinephrine and serotonin into axon terminals and may block some subtypes of serotonin, adrenergic, and histamine receptors. However the mechanism of their antidepressant effects is not clear because the therapeutic effects usually take weeks to develop and may reflect compensatory changes in the central nervous system.
| Descriptor ID |
D000929
|
| MeSH Number(s) |
D27.505.954.427.700.122.055
|
| Concept/Terms |
Antidepressive Agents, Tricyclic- Antidepressive Agents, Tricyclic
- Tricyclic Antidepressive Agents
- Agents, Tricyclic Antidepressive
- Antidepressant Drugs, Tricyclic
- Drugs, Tricyclic Antidepressant
- Tricyclic Antidepressant Drugs
- Antidepressants, Tricyclic
- Tricyclic Antidepressants
|
Below are MeSH descriptors whose meaning is more general than "Antidepressive Agents, Tricyclic".
Below are MeSH descriptors whose meaning is more specific than "Antidepressive Agents, Tricyclic".
This graph shows the total number of publications written about "Antidepressive Agents, Tricyclic" by people in this website by year, and whether "Antidepressive Agents, Tricyclic" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antidepressive Agents, Tricyclic" by people in Profiles.
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Chronic desipramine treatment alters tyrosine hydroxylase but not norepinephrine transporter immunoreactivity in norepinephrine axons in the rat prefrontal cortex. Int J Neuropsychopharmacol. 2011 Oct; 14(9):1219-32.
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Evaluation and treatment of enuresis. Am Fam Physician. 2008 Aug 15; 78(4):489-96.
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Coadministration of nefazodone and desipramine: a pharmacokinetic interaction study. J Pak Med Assoc. 2007 May; 57(5):230-5.
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Low dosage tricyclic antidepressants in depression. Evidence to change current guidelines is insufficient. BMJ. 2003 Mar 01; 326(7387):499; author reply 499.
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Review of cardiovascular effects of fluoxetine, a selective serotonin reuptake inhibitor, compared to tricyclic antidepressants. Curr Med Chem. 1998 Oct; 5(5):381-90.