"Aldehyde Reductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the oxidation of an aldose to an alditol. It possesses broad specificity for many aldoses. EC 1.1.1.21.
| Descriptor ID |
D000449
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| MeSH Number(s) |
D08.811.682.047.150.700.156.500 D08.811.682.047.820.284.500
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Aldehyde Reductase".
Below are MeSH descriptors whose meaning is more specific than "Aldehyde Reductase".
This graph shows the total number of publications written about "Aldehyde Reductase" by people in this website by year, and whether "Aldehyde Reductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Aldehyde Reductase" by people in Profiles.
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Addressing selectivity issues of aldose reductase 2 inhibitors for the management of diabetic complications. Future Med Chem. 2020 07; 12(14):1327-1358.
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Search for non-acidic ALR2 inhibitors: Evaluation of flavones as targeted agents for the management of diabetic complications. Bioorg Chem. 2020 03; 96:103570.
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Identification of 2-benzoxazolinone derivatives as lead against molecular targets of diabetic complications. Chem Biol Drug Des. 2018 12; 92(6):1981-1987.
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Aldose reductase meets histone acetylation: a new role for an old player. Diabetes. 2014 Feb; 63(2):402-4.
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Wax ester synthesis is required for Mycobacterium tuberculosis to enter in vitro dormancy. PLoS One. 2012; 7(12):e51641.
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Characterization of mouse short-chain aldehyde reductase (SCALD), an enzyme regulated by sterol regulatory element-binding proteins. J Biol Chem. 2003 Aug 22; 278(34):32380-9.
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Glucose-specific regulation of aldose reductase in human retinal pigment epithelial cells in vitro. Invest Ophthalmol Vis Sci. 2000 May; 41(6):1554-60.
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Glucose transporters control gene expression of aldose reductase, PKCalpha, and GLUT1 in mesangial cells in vitro. Am J Physiol. 1999 07; 277(1):F97-104.
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Glucose-specific regulation of aldose reductase in capan-1 human pancreatic duct cells In vitro. J Clin Invest. 1997 Oct 01; 100(7):1685-92.
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In vivo osmoregulation of aldose reductase mRNA, protein, and sorbitol in renal medulla. Am J Physiol. 1990 Jan; 258(1 Pt 2):F154-61.