"Acetazolamide" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)
Descriptor ID |
D000086
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MeSH Number(s) |
D02.886.675.867.060 D03.383.129.708.867.060
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Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Acetazolamide".
Below are MeSH descriptors whose meaning is more specific than "Acetazolamide".
This graph shows the total number of publications written about "Acetazolamide" by people in this website by year, and whether "Acetazolamide" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2003 | 0 | 1 | 1 |
2008 | 0 | 1 | 1 |
2009 | 1 | 1 | 2 |
2013 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Acetazolamide" by people in Profiles.
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Safety and Tolerability of Acetazolamide in the Idiopathic Intracranial Hypertension Treatment Trial. J Neuroophthalmol. 2016 Mar; 36(1):13-9.
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Risk factors for poor visual outcome in patients with idiopathic intracranial hypertension. Neurology. 2015 Sep 01; 85(9):799-805.
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Acetazolamide in critically ill neonates and children with metabolic alkalosis. Ann Pharmacother. 2013 Sep; 47(9):1130-5.
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Progressive optic neuropathy in idiopathic intracranial hypertension after optic nerve sheath fenestration. J Neuroophthalmol. 2009 Dec; 29(4):281-3.
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Acetazolamide as an adjunct to CPAP treatment: a case of complex sleep apnea in a patient on long-acting opioid therapy. J Clin Sleep Med. 2009 Feb 15; 5(1):63-4.
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Intracranial hypertension in systemic lupus erythematosus. Semin Ophthalmol. 2008 Mar-Apr; 23(2):127-33.
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Pseudotumor cerebri in idiopathic aplastic anemia. J AAPOS. 2003 Feb; 7(1):71-4.
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Visual loss in pseudotumor cerebri from branch retinal artery occlusion. Am J Ophthalmol. 1992 Mar 15; 113(3):334-6.
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Acetazolamide in the treatment of abnormal oculovestibular response. Am J Ophthalmol. 1991 Feb 15; 111(2):215-20.