"Acetylcysteine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The N-acetyl derivative of CYSTEINE. It is used as a mucolytic agent to reduce the viscosity of mucous secretions. It has also been shown to have antiviral effects in patients with HIV due to inhibition of viral stimulation by reactive oxygen intermediates.
| Descriptor ID |
D000111
|
| MeSH Number(s) |
D02.886.030.230.259 D12.125.166.230.259
|
| Concept/Terms |
Acetylcysteine- Acetylcysteine
- N-Acetyl-L-cysteine
- N Acetyl L cysteine
- N-Acetylcysteine
- N Acetylcysteine
- Mercapturic Acid
- Acid, Mercapturic
Acetylcysteine Sodium- Acetylcysteine Sodium
- Sodium, Acetylcysteine
- Acetylcysteine, Monosodium Salt
- Monosodium Salt Acetylcysteine
Fluprowit- Fluprowit
- Optipect Hustengetränk
- Hustengetränk, Optipect
- Muco Sanigen
- Sanigen, Muco
|
Below are MeSH descriptors whose meaning is more general than "Acetylcysteine".
Below are MeSH descriptors whose meaning is more specific than "Acetylcysteine".
This graph shows the total number of publications written about "Acetylcysteine" by people in this website by year, and whether "Acetylcysteine" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 5 | 0 | 5 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2020 | 2 | 0 | 2 |
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Below are the most recent publications written about "Acetylcysteine" by people in Profiles.
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Influence of N-acetylcysteine on steroidogenesis and gene expression in porcine placental trophoblast cells. Theriogenology. 2021 Feb; 161:49-56.
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Possible role for acetylcysteine as a treatment for acute liver failure secondary to antitubercular medication use. Am J Health Syst Pharm. 2020 09 04; 77(18):1482-1487.
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Bile acids regulate cysteine catabolism and glutathione regeneration to modulate hepatic sensitivity to oxidative injury. JCI Insight. 2018 04 19; 3(8).
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N-Acetylcysteine: an old drug, a new insight, a potentially effective treatment for thrombotic thrombocytopenic purpura. Transfusion. 2014 May; 54(5):1205-7.
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N-Acetylcysteine Protection in COPD: An Alternative Mechanism of Action. Chest. 2014 Jan; 145(1):193-4.
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Energy, oxidative stress, and inflammation in the colon. Dig Dis Sci. 2013 Dec; 58(12):3386-8.
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N-acetylcysteine rescue protocol for nephrotoxicity in children caused by ifosfamide. J Popul Ther Clin Pharmacol. 2013; 20(2):e132-45.
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Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide. Free Radic Biol Med. 2012 Jul 01; 53(1):172-81.
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Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia. Am J Physiol Heart Circ Physiol. 2011 Apr; 300(4):H1133-40.
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N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death. Cancer Lett. 2010 Dec 08; 298(2):186-94.