"Baclofen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
| Descriptor ID |
D001418
|
| MeSH Number(s) |
D02.241.081.114.500.350.100
|
| Concept/Terms |
Baclofen- Baclofen
- Baclophen
- PCP-GABA
- beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
- Chlorophenyl GABA
- GABA, Chlorophenyl
- beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
Ba-34,647- Ba-34,647
- Ba34,647
- Ba-34647
- Ba34647
- CIBA-34,647-BA
- CIBA34,647BA
|
Below are MeSH descriptors whose meaning is more general than "Baclofen".
Below are MeSH descriptors whose meaning is more specific than "Baclofen".
This graph shows the total number of publications written about "Baclofen" by people in this website by year, and whether "Baclofen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 1 | 0 | 1 |
| 2018 | 1 | 2 | 3 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
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Below are the most recent publications written about "Baclofen" by people in Profiles.
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Characterization of standard work tools for intrathecal baclofen therapy. Childs Nerv Syst. 2021 10; 37(10):3073-3081.
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The effect of baclofen on objective and subjective sleep measures in a model of transient insomnia. Sleep Med. 2020 08; 72:130-134.
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Neurosurgical Management of Spastic Conditions of the Upper Extremity. Hand Clin. 2018 Nov; 34(4):547-554.
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Placement of baclofen pump catheter through a C1-2 puncture: technical note. J Neurosurg Pediatr. 2018 04; 21(4):389-394.
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A standardized protocol to reduce pediatric baclofen pump infections: a quality improvement initiative. J Neurosurg Pediatr. 2018 04; 21(4):395-400.
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The effect of baclofen on nocturnal gastroesophageal reflux and measures of sleep quality: a randomized, cross-over trial. Neurogastroenterol Motil. 2012 Jun; 24(6):553-9, e253.