"Half-Life" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, 
	MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, 
	which enables searching at various levels of specificity.
	
	
		
			
			
				The time it takes for a substance (drug, radioactive nuclide, or other) to lose half of its pharmacologic, physiologic, or radiologic activity.
    
			
			
				
				
					
						| Descriptor ID | D006207 | 
					
						| MeSH Number(s) | G01.910.405 | 
					
						| Concept/Terms | Half-LifeHalf-LifeHalf LifeHalf-LifesHalflifeHalflifes
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				Below are MeSH descriptors whose meaning is more general than "Half-Life".
				
			 
			
			
				Below are MeSH descriptors whose meaning is more specific than "Half-Life".
				
			 
		 
	 
 
                                        
                                            
	
	
		
			
			
					
				This graph shows the total number of publications written about "Half-Life" by people in this website by year, and whether "Half-Life" was a major or minor topic of these publications. 
				
					 
                    To see the data from this visualization as text, 
click here. 
                
		            | Year | Major Topic | Minor Topic | Total | 
|---|
| 1995 | 0 | 2 | 2 | 
| 2002 | 0 | 2 | 2 | 
| 2003 | 0 | 2 | 2 | 
| 2004 | 0 | 1 | 1 | 
| 2005 | 0 | 2 | 2 | 
| 2006 | 0 | 1 | 1 | 
| 2007 | 0 | 2 | 2 | 
| 2009 | 0 | 1 | 1 | 
| 2010 | 0 | 1 | 1 | 
| 2012 | 0 | 2 | 2 | 
| 2013 | 0 | 3 | 3 | 
| 2014 | 0 | 2 | 2 | 
| 2015 | 0 | 1 | 1 | 
| 2016 | 0 | 1 | 1 | 
| 2018 | 0 | 1 | 1 | 
| 2019 | 0 | 1 | 1 | 
| 2020 | 0 | 1 | 1 | 
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				Below are the most recent publications written about "Half-Life" by people in Profiles.
						
					
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								Vaginal Suppositories Containing SHetA2 to Treat Cervical Dysplasia: Pharmacokinetics of Daily Doses and Preliminary Safety Profile. J Pharm Sci. 2020 06; 109(6):2000-2008. 
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								Convergence of Cell Pharmacology and Drug Delivery. Stem Cells Transl Med. 2019 09; 8(9):874-879. 
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								Influence of the estrus cycle of the mouse on the disposition of SHetA2 after vaginal administration. Eur J Pharm Biopharm. 2018 Sep; 130:272-280. 
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								Extended half-life factor VIII for immune tolerance induction in haemophilia. Haemophilia. 2016 Nov; 22(6):e552-e554. 
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								An In Vitro Thrombolysis Study Using a Mixture of Fast-Acting and Slower Release Microspheres. Pharm Res. 2016 07; 33(7):1552-63. 
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								Safety, pharmacokinetics and neutralization of the broadly neutralizing HIV-1 human monoclonal antibody VRC01 in healthy adults. Clin Exp Immunol. 2015 Dec; 182(3):289-301. 
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								Liposomes modified with superhydrophilic polymer linked to a nonphospholipid anchor exhibit reduced complement activation and enhanced circulation. J Pharm Sci. 2015 Jan; 104(1):114-23. 
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								Tuning pharmacokinetics and biodistribution of a targeted drug delivery system through incorporation of a passive targeting component. Sci Rep. 2014 Jul 11; 4:5669. 
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								Dolutegravir, a second-generation integrase inhibitor for the treatment of HIV-1 infection. Ann Pharmacother. 2014 Mar; 48(3):395-403. 
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								Monocarboxylate transporter mediated uptake of moxifloxacin on human retinal pigmented epithelium cells. J Pharm Pharmacol. 2014 Apr; 66(4):574-83.