"HLA-D Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Human immune-response or Class II antigens found mainly, but not exclusively, on B-lymphocytes and produced from genes of the HLA-D locus. They are extremely polymorphic families of glycopeptides, each consisting of two chains, alpha and beta. This group of antigens includes the -DR, -DQ and -DP designations, of which HLA-DR is most studied; some of these glycoproteins are associated with certain diseases, possibly of immune etiology.
| Descriptor ID |
D006681
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| MeSH Number(s) |
D12.776.395.550.509.400 D12.776.543.550.440.400 D23.050.301.500.400.400 D23.050.301.500.450.400 D23.050.705.552.410.400 D23.050.705.552.450.400
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| Concept/Terms |
HLA-D Antigens- HLA-D Antigens
- HLA D Antigens
- Human Class II Antigens
- HLA-D
- HLA-Dw Antigens
- Antigens, HLA-Dw
- HLA Dw Antigens
- Antigens, HLA-D
- Antigens, HLA D
- Immune Response-Associated Antigens, Human
- Class II Human Antigens
- Ia-Like Antigens, Human
- Antigens, Human Ia-Like
- Human Ia-Like Antigens
- Ia Like Antigens, Human
- Immune-Associated Antigens, Human
- Antigens, Human Immune-Associated
- Human Immune-Associated Antigens
- Immune Associated Antigens, Human
- Immune-Response Antigens, Human
- Antigens, Human Immune-Response
- Human Immune-Response Antigens
- Immune Response Antigens, Human
- Immune Response Associated Antigens, Human
- HLA-Dw
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Below are MeSH descriptors whose meaning is more general than "HLA-D Antigens".
Below are MeSH descriptors whose meaning is more specific than "HLA-D Antigens".
This graph shows the total number of publications written about "HLA-D Antigens" by people in this website by year, and whether "HLA-D Antigens" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "HLA-D Antigens" by people in Profiles.
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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity. Elife. 2016 Feb 15; 5.
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A high degree of HLA disparity arises from limited allelic diversity: analysis of 1775 unrelated bone marrow transplant donor-recipient pairs. Hum Immunol. 2007 Jan; 68(1):30-40.
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Variation in HLA-DM expression influences conversion of MHC class II alpha beta:class II-associated invariant chain peptide complexes to mature peptide-bound class II alpha beta dimers in a normal B cell line. J Immunol. 1996 Mar 15; 156(6):2196 - 2204.
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Genetic markers in familial narcolepsy. Sleep. 1991 Jun; 14(3):270-1.