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GPCR agonist-induced transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin-resistant rats.
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GPCR agonist-induced transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin-resistant rats.
GPCR agonist-induced transactivation of the EGFR upregulates MLC II expression and promotes hypertension in insulin-resistant rats. Cardiovasc Res. 2010 Jul 01; 87(1):177-86.
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PubMed
subject areas
Adrenergic alpha-1 Receptor Agonists
Adrenergic alpha-Agonists
Animals
Cardiac Myosins
Cells, Cultured
Disease Models, Animal
ErbB Receptors
Extracellular Signal-Regulated MAP Kinases
Fructose
Hypertension
Insulin Resistance
Male
Matrix Metalloproteinase 2
Matrix Metalloproteinase 7
Matrix Metalloproteinase Inhibitors
Muscle, Smooth, Vascular
Myocytes, Smooth Muscle
Myosin Light Chains
p38 Mitogen-Activated Protein Kinases
Phenylephrine
Phosphorylation
Protease Inhibitors
Protein Kinase Inhibitors
Rats
Rats, Wistar
Receptor Cross-Talk
Receptors, Adrenergic, alpha-1
RNA Interference
Signal Transduction
Time Factors
Transfection
Up-Regulation
Vasoconstriction
authors with profiles
Prabhakara R Nagareddy