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Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.
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Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia.
Inhibition of NEDD8-activating enzyme: a novel approach for the treatment of acute myeloid leukemia. Blood. 2010 May 06; 115(18):3796-800.
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PubMed
subject areas
Animals
Blotting, Western
Cell Line, Tumor
Cullin Proteins
Cyclopentanes
DNA Damage
Fluorescent Antibody Technique
fms-Like Tyrosine Kinase 3
Humans
Leukemia, Myeloid, Acute
Mice
NEDD8 Protein
NF-kappa B
Proteasome Endopeptidase Complex
Proteasome Inhibitors
Pyrimidines
Reactive Oxygen Species
Reverse Transcriptase Polymerase Chain Reaction
RNA, Messenger
Signal Transduction
Ubiquitins
Xenograft Model Antitumor Assays
authors with profiles
Michael Joseph O'Dwyer