"Kernicterus" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
| Descriptor ID |
D007647
|
| MeSH Number(s) |
C10.228.140.163.480 C15.378.295.502 C16.614.304.502 C18.452.132.480 C20.306.502 C23.550.429.750
|
| Concept/Terms |
Kernicterus- Kernicterus
- Encephalopathy, Bilirubin
- Bilirubin Encephalopathy
- Bilirubin Encephalopathies
- Encephalopathies, Bilirubin
- Hyperbilirubinemic Encephalopathy
- Encephalopathies, Hyperbilirubinemic
- Hyperbilirubinemic Encephalopathies
- Encephalopathy, Hyperbilirubinemic
|
Below are MeSH descriptors whose meaning is more general than "Kernicterus".
- Diseases [C]
- Nervous System Diseases [C10]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Brain Diseases, Metabolic [C10.228.140.163]
- Kernicterus [C10.228.140.163.480]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Erythroblastosis, Fetal [C15.378.295]
- Kernicterus [C15.378.295.502]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Infant, Newborn, Diseases [C16.614]
- Erythroblastosis, Fetal [C16.614.304]
- Kernicterus [C16.614.304.502]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- Brain Diseases, Metabolic [C18.452.132]
- Kernicterus [C18.452.132.480]
- Immune System Diseases [C20]
- Erythroblastosis, Fetal [C20.306]
- Kernicterus [C20.306.502]
- Pathological Conditions, Signs and Symptoms [C23]
- Pathologic Processes [C23.550]
- Hyperbilirubinemia [C23.550.429]
- Kernicterus [C23.550.429.750]
Below are MeSH descriptors whose meaning is more specific than "Kernicterus".
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Below are the most recent publications written about "Kernicterus" by people in Profiles.