"Levodopa" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The naturally occurring form of DIHYDROXYPHENYLALANINE and the immediate precursor of DOPAMINE. Unlike dopamine itself, it can be taken orally and crosses the blood-brain barrier. It is rapidly taken up by dopaminergic neurons and converted to DOPAMINE. It is used for the treatment of PARKINSONIAN DISORDERS and is usually given with agents that inhibit its conversion to dopamine outside of the central nervous system.
| Descriptor ID |
D007980
|
| MeSH Number(s) |
D02.092.311.200.480 D12.125.072.050.685.400.500 D12.125.072.050.875.130.500
|
| Concept/Terms |
Levodopa- Levodopa
- L-Dopa
- L Dopa
- 3-Hydroxy-L-tyrosine
- 3 Hydroxy L tyrosine
- L-3,4-Dihydroxyphenylalanine
- L 3,4 Dihydroxyphenylalanine
|
Below are MeSH descriptors whose meaning is more general than "Levodopa".
Below are MeSH descriptors whose meaning is more specific than "Levodopa".
This graph shows the total number of publications written about "Levodopa" by people in this website by year, and whether "Levodopa" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
| 2019 | 1 | 1 | 2 |
To return to the timeline,
click here.
Below are the most recent publications written about "Levodopa" by people in Profiles.
-
Neurochemical supplementation in patients with depressed levels of participation after brain tumor surgery: Rationale and preliminary results. J Clin Neurosci. 2020 Jan; 71:93-96.
-
Pharmacological Management of Dementia with Lewy Bodies. Drugs Aging. 2019 04; 36(4):309-319.
-
A randomized trial of levodopa as treatment for residual amblyopia in older children. Ophthalmology. 2015 May; 122(5):874-81.
-
Role for a6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice. Neuropharmacology. 2012 Sep; 63(3):450-9.
-
Evolution of pigment cell regression in the cavefish Astyanax: a late step in melanogenesis. Evol Dev. 2004 Jul-Aug; 6(4):209-18.
-
Serotonin plays an early role in the metamorphosis of the hydrozoan Phialidium gregarium. Dev Biol. 1997 Oct 15; 190(2):229-40.
-
Growth hormone restores protein synthesis in skeletal muscle of old male rats. J Gerontol. 1985 Nov; 40(6):689-94.
-
L-dopa restores amplitude of growth hormone pulses in old male rats to that observed in young male rats. Neuroendocrinology. 1982 Mar; 34(3):163-8.
-
Maintenance by L-DOPA treatment of estrous cycles and LH response to estrogen in aging female rats. Exp Aging Res. 1980 Dec; 6(6):547-54.