Item Type | Name |
Concept
|
Ammonia
|
Concept
|
Ammonia-Lyases
|
Concept
|
Ammonium Sulfate
|
Concept
|
Adenosine Triphosphate
|
Concept
|
Adult
|
Concept
|
Anions
|
Concept
|
Haplorhini
|
Concept
|
Aged
|
Concept
|
Alcaligenes
|
Concept
|
Alcohol Dehydrogenase
|
Concept
|
Alcohol Oxidoreductases
|
Concept
|
Aldehyde Oxidoreductases
|
Concept
|
Aldehyde Reductase
|
Concept
|
Algorithms
|
Concept
|
Cadmium
|
Concept
|
Protein-Arginine Deiminases
|
Concept
|
Acetates
|
Concept
|
Acetyl Coenzyme A
|
Concept
|
Acetylation
|
Concept
|
Acids
|
Concept
|
Acrylates
|
Concept
|
Carbohydrate Dehydrogenases
|
Concept
|
Amides
|
Concept
|
Amidohydrolases
|
Concept
|
Amino Acid Oxidoreductases
|
Concept
|
Amino Acid Sequence
|
Concept
|
Acyl Coenzyme A
|
Concept
|
Carbon Isotopes
|
Concept
|
Carbon Radioisotopes
|
Concept
|
Carboxy-Lyases
|
Concept
|
Carboxylic Acids
|
Concept
|
Cyclic AMP
|
Concept
|
Adenosine Deaminase
|
Concept
|
Adenosine Diphosphate
|
Concept
|
Adenosine Diphosphate Ribose
|
Concept
|
Adenosine Monophosphate
|
Concept
|
Bacillus anthracis
|
Concept
|
Bacillus subtilis
|
Concept
|
Blood Pressure
|
Concept
|
Career Mobility
|
Concept
|
Base Sequence
|
Concept
|
Borates
|
Concept
|
Cations, Divalent
|
Concept
|
Cations, Monovalent
|
Concept
|
Cattle
|
Concept
|
Benzoates
|
Concept
|
Cell Adhesion
|
Concept
|
Cell Line
|
Concept
|
Buffers
|
Concept
|
Cytosol
|
Concept
|
Decarboxylation
|
Concept
|
Computer Simulation
|
Concept
|
Computers
|
Concept
|
Biophysics
|
Concept
|
Biopsy
|
Concept
|
Biotin
|
Concept
|
Chromatography, Agarose
|
Concept
|
Chromatography, Gel
|
Concept
|
Creatine Kinase
|
Concept
|
Deuterium
|
Concept
|
Diabetes Mellitus
|
Concept
|
Crystallography
|
Concept
|
Cobalt
|
Concept
|
Cyclodextrins
|
Concept
|
Cyclohexanols
|
Concept
|
Coenzyme A
|
Concept
|
Coenzymes
|
Concept
|
Cysteine
|
Concept
|
Cysteine Synthase
|
Concept
|
Cold Temperature
|
Concept
|
Colorado
|
Concept
|
Energy Transfer
|
Concept
|
Enterobacteriaceae
|
Concept
|
Dose-Response Relationship, Drug
|
Concept
|
Drosophila melanogaster
|
Concept
|
Fibrin
|
Concept
|
Fibrinolysin
|
Concept
|
Drug Evaluation, Preclinical
|
Concept
|
Escherichia coli
|
Concept
|
Education, Nursing, Continuing
|
Concept
|
Hexokinase
|
Concept
|
Ethylmaleimide
|
Concept
|
Guanosine Triphosphate
|
Concept
|
Guinea Pigs
|
Concept
|
Haemophilus influenzae
|
Concept
|
Electron Spin Resonance Spectroscopy
|
Concept
|
Electron Transport
|
Concept
|
Horses
|
Concept
|
Health Facility Environment
|
Concept
|
Health Maintenance Organizations
|
Concept
|
Humans
|
Concept
|
Hydro-Lyases
|
Concept
|
Hydrogen
|
Concept
|
Hydrogen Bonding
|
Concept
|
Genes, Bacterial
|
Concept
|
Genes, Fungal
|
Concept
|
Gluconates
|
Concept
|
Glucosephosphate Dehydrogenase
|
Concept
|
Liver
|
Concept
|
Oxo-Acid-Lyases
|
Concept
|
Ketoglutaric Acids
|
Concept
|
Glucose-6-Phosphate Isomerase
|
Concept
|
Glucuronates
|
Concept
|
Glutamate Dehydrogenase
|
Concept
|
Glutamates
|
Concept
|
Glutamine
|
Concept
|
Glutathione
|
Concept
|
Glutathione Transferase
|
Concept
|
Glycerolphosphate Dehydrogenase
|
Concept
|
Glycoside Hydrolases
|
Concept
|
Lysine
|
Concept
|
Glycosylation
|
Concept
|
Glyoxylates
|
Concept
|
L-Lactate Dehydrogenase
|
Concept
|
Magnesium
|
Concept
|
Malate Dehydrogenase
|
Concept
|
Malates
|
Concept
|
Maleates
|
Concept
|
Malonates
|
Concept
|
Mandelic Acids
|
Concept
|
Manganese
|
Concept
|
Inosine Triphosphate
|
Concept
|
Fabaceae
|
Concept
|
Niacinamide
|
Concept
|
Muscles
|
Concept
|
Nitrobenzenes
|
Concept
|
Nitrobenzoates
|
Concept
|
Nitrogen Isotopes
|
Concept
|
Intestinal Mucosa
|
Concept
|
Myocardium
|
Concept
|
Norleucine
|
Concept
|
NAD
|
Concept
|
NADP
|
Concept
|
Nucleoside Deaminases
|
Concept
|
Iron
|
Concept
|
Naphthols
|
Concept
|
Nucleotides
|
Concept
|
Isocitrate Dehydrogenase
|
Concept
|
Isocitrates
|
Concept
|
Isoelectric Point
|
Concept
|
Isomerism
|
Concept
|
Nursing Staff
|
Concept
|
Job Satisfaction
|
Concept
|
Plants
|
Concept
|
Plants, Medicinal
|
Concept
|
Plasminogen
|
Concept
|
Poly Adenosine Diphosphate Ribose
|
Concept
|
Poly(ADP-ribose) Polymerases
|
Concept
|
Middle Aged
|
Concept
|
Phenylalanine
|
Concept
|
Mitochondria
|
Concept
|
Models, Structural
|
Concept
|
Phosphates
|
Concept
|
Phosphoadenosine Phosphosulfate
|
Concept
|
Phosphocreatine
|
Concept
|
Phosphofructokinase-1
|
Concept
|
Phosphogluconate Dehydrogenase
|
Concept
|
Potassium
|
Concept
|
Potassium Chloride
|
Concept
|
Molecular Sequence Data
|
Concept
|
Phosphoric Monoester Hydrolases
|
Concept
|
Phosphopeptides
|
Concept
|
Phosphoric Acids
|
Concept
|
Phosphorus Isotopes
|
Concept
|
Phosphorus Radioisotopes
|
Concept
|
Phosphorylation
|
Concept
|
Phosphotransferases
|
Concept
|
Motivation
|
Concept
|
Phylogeny
|
Concept
|
Precipitin Tests
|
Concept
|
Pregnancy
|
Concept
|
Pichia
|
Concept
|
Columbidae
|
Concept
|
Piperidones
|
Concept
|
Saccharomyces cerevisiae
|
Concept
|
Saccharopine Dehydrogenases
|
Concept
|
Salaries and Fringe Benefits
|
Concept
|
Regression Analysis
|
Concept
|
Salmonella typhimurium
|
Concept
|
Patient Education as Topic
|
Concept
|
Retrospective Studies
|
Concept
|
L-Serine Dehydratase
|
Concept
|
Peptide Fragments
|
Concept
|
Peptides
|
Concept
|
Risk Factors
|
Concept
|
Sheep
|
Concept
|
Periodicals as Topic
|
Concept
|
Thymus Gland
|
Concept
|
Swine
|
Concept
|
Pyridoxal
|
Concept
|
Pyridoxal Phosphate
|
Concept
|
Pyridoxamine
|
Concept
|
Diphosphates
|
Concept
|
Pyruvates
|
Concept
|
Tartrates
|
Concept
|
Tartronates
|
Concept
|
Rabbits
|
Concept
|
Temperature
|
Concept
|
Program Evaluation
|
Concept
|
Thiadiazoles
|
Concept
|
Thiocyanates
|
Concept
|
Nursing Evaluation Research
|
Concept
|
Nursing Methodology Research
|
Concept
|
Zinc
|
Concept
|
2-Aminoadipic Acid
|
Concept
|
2,6-Dichloroindophenol
|
Concept
|
HIV Infections
|
Concept
|
Blotting, Western
|
Concept
|
Restriction Mapping
|
Concept
|
Drug Design
|
Concept
|
Stereoisomerism
|
Concept
|
Ascaris suum
|
Concept
|
Structure-Activity Relationship
|
Concept
|
Molecular Probes
|
Concept
|
Students, Nursing
|
Concept
|
Subcellular Fractions
|
Concept
|
Genes, Helminth
|
Concept
|
Succinates
|
Concept
|
Sugar Alcohol Dehydrogenases
|
Concept
|
Sulfates
|
Concept
|
Sulfides
|
Concept
|
Sulfonamides
|
Concept
|
Sulfur
|
Concept
|
Glycosylphosphatidylinositols
|
Concept
|
Point Mutation
|
Concept
|
Arabidopsis
|
Concept
|
Sequence Homology, Amino Acid
|
Concept
|
Pseudomonas putida
|
Concept
|
Protein Structure, Secondary
|
Concept
|
Protein Structure, Tertiary
|
Concept
|
Patient Satisfaction
|
Concept
|
Vitamin K
|
Concept
|
Risk Assessment
|
Concept
|
Mutagenesis, Site-Directed
|
Concept
|
Frail Elderly
|
Concept
|
Open Reading Frames
|
Concept
|
Glutamic Acid
|
Concept
|
GTP-Binding Proteins
|
Concept
|
Acrylamide
|
Concept
|
Mutation, Missense
|
Concept
|
Catalytic Domain
|
Concept
|
Hyphomicrobium
|
Concept
|
Leukotriene C4
|
Concept
|
Combinatorial Chemistry Techniques
|
Concept
|
Protein Renaturation
|
Concept
|
Glucuronic Acid
|
Concept
|
Crystallography, X-Ray
|
Concept
|
Phenol
|
Concept
|
Succinic Acid
|
Concept
|
Sodium Azide
|
Concept
|
Hydroxylamine
|
Concept
|
Amino Acid Substitution
|
Concept
|
Probability
|
Concept
|
Dihydrouracil Dehydrogenase (NADP)
|
Concept
|
Proline
|
Concept
|
Propionibacterium
|
Concept
|
Nurse's Role
|
Concept
|
Drug Resistance, Bacterial
|
Concept
|
Phosphofructokinases
|
Concept
|
Protein Denaturation
|
Concept
|
Protein Kinases
|
Concept
|
Transglutaminases
|
Concept
|
Phosphofructokinase-2
|
Concept
|
Protons
|
Concept
|
Pseudomonas
|
Concept
|
Carboxypeptidase B2
|
Concept
|
Pterins
|
Concept
|
Electron-Transferring Flavoproteins
|
Concept
|
2-Aminoadipate Transaminase
|
Concept
|
Mice
|
Concept
|
Rats
|
Concept
|
Sodium
|
Concept
|
Sodium Chloride
|
Concept
|
Software
|
Concept
|
Spectrometry, Fluorescence
|
Concept
|
Tricarboxylic Acids
|
Concept
|
Triose-Phosphate Isomerase
|
Concept
|
Tritium
|
Concept
|
Tryptophan Synthase
|
Concept
|
Uracil
|
Concept
|
Quality Improvement
|
Concept
|
Gene Expression
|
Concept
|
Comorbidity
|
Concept
|
Logistic Models
|
Concept
|
Case-Control Studies
|
Concept
|
Mutagenesis, Insertional
|
Concept
|
alpha-Cyclodextrins
|
Concept
|
Intracellular Signaling Peptides and Proteins
|
Concept
|
Total Quality Management
|
Concept
|
Phosphotransferases (Alcohol Group Acceptor)
|
Concept
|
Cyclic AMP-Dependent Protein Kinases
|
Concept
|
NIH 3T3 Cells
|
Concept
|
DNA Primers
|
Concept
|
Dimerization
|
Concept
|
Pyruvic Acid
|
Concept
|
Computational Biology
|
Concept
|
Alanine Dehydrogenase
|
Concept
|
Mitogen-Activated Protein Kinases
|
Concept
|
Oxaloacetic Acid
|
Concept
|
Organic Chemistry Phenomena
|
Concept
|
Young Adult
|
Concept
|
ortho-Aminobenzoates
|
Concept
|
Smoking Prevention
|
Concept
|
Apoenzymes
|
Concept
|
Arginine
|
Concept
|
Ascaris
|
Concept
|
Asparagine
|
Concept
|
Aspartate Aminotransferases
|
Concept
|
Aspartate Ammonia-Lyase
|
Concept
|
Aspartic Acid
|
Concept
|
Cell Wall
|
Concept
|
Cells, Cultured
|
Concept
|
Chickens
|
Concept
|
Chlorides
|
Concept
|
Diacetyl
|
Concept
|
Diamines
|
Concept
|
Diazooxonorleucine
|
Concept
|
Dictyostelium
|
Concept
|
Diethyl Pyrocarbonate
|
Concept
|
Dihydroorotase
|
Concept
|
Dihydropteroate Synthase
|
Concept
|
Dimethylformamide
|
Concept
|
Dipeptidases
|
Concept
|
Disulfides
|
Concept
|
Dithionitrobenzoic Acid
|
Concept
|
Flavins
|
Concept
|
Fluorescence
|
Concept
|
Fluorescence Polarization
|
Concept
|
Fluorometry
|
Concept
|
Formate Dehydrogenases
|
Concept
|
Formates
|
Concept
|
Fructose-Bisphosphate Aldolase
|
Concept
|
Fumarate Hydratase
|
Concept
|
Fumarates
|
Concept
|
gamma-Glutamyltransferase
|
Concept
|
Indoles
|
Concept
|
Mass Screening
|
Concept
|
Metals, Rare Earth
|
Concept
|
Methionine
|
Concept
|
Oligopeptides
|
Concept
|
Oncology Nursing
|
Concept
|
Osmosis
|
Concept
|
Oxalates
|
Concept
|
Oxaloacetates
|
Concept
|
Oxidation-Reduction
|
Concept
|
Oxygen
|
Concept
|
Oxygen Isotopes
|
Concept
|
4-Aminobenzoic Acid
|
Academic Article
|
Glutamate 325 is a general acid-base catalyst in the reaction catalyzed by fructose-2,6-bisphosphatase.
|
Academic Article
|
Pyridoxal 5'-phosphate-dependent alpha,beta-elimination reactions: mechanism of O-acetylserine sulfhydrylase.
|
Academic Article
|
Dihydropyrimidine amidohydrolases and dihydroorotases share the same origin and several enzymatic properties.
|
Academic Article
|
Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification.
|
Academic Article
|
Kinetic analysis of YPD1-dependent phosphotransfer reactions in the yeast osmoregulatory phosphorelay system.
|
Academic Article
|
Purification and properties of beta-alanine synthase from calf liver.
|
Academic Article
|
A three-dimensional homology model of the O-acetylserine sulfhydrylase-B from Salmonella typhimurium.
|
Academic Article
|
Optimum activity of the phosphofructokinase from Ascaris suum requires more than one metal ion.
|
Academic Article
|
Acid-base chemical mechanism of homocitrate synthase from Saccharomyces cerevisiae.
|
Academic Article
|
Overall kinetic mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Role of the S128, H186, and N187 triad in substrate binding and decarboxylation in the sheep liver 6-phosphogluconate dehydrogenase reaction.
|
Academic Article
|
Determinants of substrate specificity for saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: comparison of A and B isozymes.
|
Academic Article
|
Proper positioning of the nicotinamide ring is crucial for the Ascaris suum malic enzyme reaction.
|
Academic Article
|
Effect of mutation of lysine-120, located at the entry to the active site of O-acetylserine sulfhydrylase-A from Salmonella typhimurium.
|
Academic Article
|
Role of Histidine-152 in cofactor orientation in the PLP-dependent O-acetylserine sulfhydrylase reaction.
|
Academic Article
|
Chemical mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Examination of intrinsic sulfonamide resistance in Bacillus anthracis: a novel assay for dihydropteroate synthase.
|
Academic Article
|
Potassium is an activator of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Isotope exchange at equilibrium indicates a steady state ordered kinetic mechanism for human sulfotransferase.
|
Academic Article
|
Evaluation of a career ladder program in an ambulatory care environment.
|
Academic Article
|
Design of O-acetylserine sulfhydrylase inhibitors by mimicking nature.
|
Academic Article
|
Glutamates 78 and 122 in the active site of saccharopine dehydrogenase contribute to reactant binding and modulate the basicity of the acid-base catalysts.
|
Academic Article
|
Reaction product affinity regulates activation of human sulfotransferase 1A1 PAP sulfation.
|
Academic Article
|
Kinetics of activated thrombin-activatable fibrinolysis inhibitor (TAFIa)-catalyzed cleavage of C-terminal lysine residues of fibrin degradation products and removal of plasminogen-binding sites.
|
Academic Article
|
The multifaceted pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase.
|
Academic Article
|
Evidence in support of lysine 77 and histidine 96 as acid-base catalytic residues in saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Utility of the theory of planned behavior to predict nursing staff blood pressure monitoring behaviours.
|
Academic Article
|
Evidence for an induced conformational change in the catalytic mechanism of homoisocitrate dehydrogenase for Saccharomyces cerevisiae: Characterization of the D271N mutant enzyme.
|
Academic Article
|
Probing the chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae using site-directed mutagenesis.
|
Academic Article
|
Kinetic mechanism of the adenosine 3',5'-monophosphate dependent protein kinase catalytic subunit in the direction of magnesium adenosine 5'-diphosphate phosphorylation.
|
Academic Article
|
Mechanism of activation of the NAD-malic enzyme from Ascaris suum by fumarate.
|
Academic Article
|
pH dependence of the absorbance and 31P NMR spectra of O-acetylserine sulfhydrylase in the absence and presence of O-acetyl-L-serine.
|
Academic Article
|
pH dependence of the kinetic parameters for the pyrophosphate-dependent phosphofructokinase reaction supports a proton-shuttle mechanism.
|
Academic Article
|
Substrate activation by malate induced by oxalate in the Ascaris suum NAD-malic enzyme reaction.
|
Academic Article
|
Chemical mechanism of the adenosine cyclic 3',5'-monophosphate dependent protein kinase from pH studies.
|
Academic Article
|
Inactivation of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii by pyridoxal 5'-phosphate. Determination of the pH dependence of enzyme-reactant dissociation constants from protection against inactivation.
|
Academic Article
|
Isotope exchange as a probe of the kinetic mechanism of pyrophosphate-dependent phosphofructokinase.
|
Academic Article
|
Kinetic mechanism of pyrophosphate-dependent phosphofructokinase from Propionibacterium freudenreichii.
|
Academic Article
|
Kinetic studies to determine the mechanism of regulation of bovine liver glutamate dehydrogenase by nucleotide effectors.
|
Academic Article
|
Acid-base chemical mechanism of aspartase from Hafnia alvei.
|
Academic Article
|
Acid-base catalytic mechanism and pH dependence of fructose 2,6-bisphosphate activation of the Ascaris suum phosphofructokinase.
|
Academic Article
|
Kinetic isotope effects as a probe of the beta-elimination reaction catalyzed by O-acetylserine sulfhydrylase.
|
Academic Article
|
Tryptophan luminescence as a probe of enzyme conformation along the O-acetylserine sulfhydrylase reaction pathway.
|
Academic Article
|
Comparison of the substrate specificities of cAMP-dependent protein kinase from bovine heart and Ascaris suum muscle.
|
Academic Article
|
Time-resolved fluorescence of O-acetylserine sulfhydrylase catalytic intermediates.
|
Academic Article
|
Ligand binding induces a large conformational change in O-acetylserine sulfhydrylase from Salmonella typhimurium.
|
Academic Article
|
Lysine 183 is the general base in the 6-phosphogluconate dehydrogenase-catalyzed reaction.
|
Academic Article
|
Substitution of pyridoxal 5'-phosphate in D-serine dehydratase from Escherichia coli by cofactor analogues provides information on cofactor binding and catalysis.
|
Academic Article
|
Initial velocity, spectral, and pH studies of the serine-glyoxylate aminotransferase from Hyphomicrobiuim methylovorum.
|
Academic Article
|
Characterization of the allosteric anion-binding site of O-acetylserine sulfhydrylase.
|
Academic Article
|
Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 A resolution.
|
Academic Article
|
Alpha,beta-elimination reaction of O-acetylserine sulfhydrylase. Is the pyridine ring required?
|
Academic Article
|
Surface-exposed tryptophan residues are essential for O-acetylserine sulfhydrylase structure, function, and stability.
|
Academic Article
|
Kinetic mechanism of the serine acetyltransferase from Haemophilus influenzae.
|
Academic Article
|
Kinetic mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
|
Academic Article
|
Role of methionine-13 in the catalytic mechanism of 6-phosphogluconate dehydrogenase from sheep liver.
|
Academic Article
|
A catalytic triad is responsible for acid-base chemistry in the Ascaris suum NAD-malic enzyme.
|
Academic Article
|
Mechanism of the addition half of the O-acetylserine sulfhydrylase-A reaction.
|
Academic Article
|
Bisubstrate inhibition: Theory and application to N-acetyltransferases.
|
Academic Article
|
A proposed proton shuttle mechanism for saccharopine dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Complete kinetic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
|
Academic Article
|
Overall kinetic mechanism of saccharopine dehydrogenase (L-glutamate forming) from Saccharomyces cerevisiae.
|
Academic Article
|
Chemical mechanism of saccharopine reductase from Saccharomyces cerevisiae.
|
Academic Article
|
(31)P NMR studies of O-acetylserine sulfhydrylase-B from Salmonella typhimurium.
|
Academic Article
|
Site-directed mutagenesis as a probe of the acid-base catalytic mechanism of homoisocitrate dehydrogenase from Saccharomyces cerevisiae.
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Academic Article
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Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation.
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Academic Article
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Identification of the structural determinants for the stability of substrate and aminoacrylate external Schiff bases in O-acetylserine sulfhydrylase-A.
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Academic Article
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Mechanism of the aromatic aminotransferase encoded by the Aro8 gene from Saccharomyces cerevisiae.
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Academic Article
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Inhibition of human ?-glutamyl transpeptidase: development of more potent, physiologically relevant, uncompetitive inhibitors.
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Academic Article
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Isozyme-specific ligands for O-acetylserine sulfhydrylase, a novel antibiotic target.
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Academic Article
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Mechanism of O-acetylserine sulfhydrylase fromSalmonella typhimurium LT-2.
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Academic Article
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Crystallization of the NAD-dependent malic enzyme from the parasitic nematode Ascaris suum.
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Academic Article
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Effector-induced conformational transitions in Ascaris suum phosphofructokinase. A fluorescence and circular dichroism study.
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Academic Article
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Fructose 2,6-bisphosphate and AMP increase the affinity of the Ascaris suum phosphofructokinase for fructose 6-phosphate in a process separate from the relief of ATP inhibition.
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Academic Article
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Correlation between hysteresis and allosteric properties for phosphofructokinase from Ascaris suum.
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Academic Article
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Reaction of Ascaris suum phosphofructokinase with diethylpyrocarbonate. Inactivation and desensitization to allosteric modulation.
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Academic Article
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Kinetic mechanism of Ascaris suum phosphofructokinase desensitized to allosteric modulation by diethylpyrocarbonate modification.
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Academic Article
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Carbohydrate substrate specificity of bacterial and plant pyrophosphate-dependent phosphofructokinases.
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Academic Article
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Kinetic studies on the activation of pyrophosphate-dependent phosphofructokinase from mung bean by fructose 2,6-bisphosphate and related compounds.
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Academic Article
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Isotope partitioning in the adenosine 3',5'-monophosphate dependent protein kinase reaction indicates a steady-state random kinetic mechanism.
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Academic Article
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The kinetic mechanism of human placental aldose reductase and aldehyde reductase II.
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Academic Article
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Use of primary deuterium and 15N isotope effects to deduce the relative rates of steps in the mechanisms of alanine and glutamate dehydrogenases.
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Academic Article
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Adenosine cyclic 3',5'-monophosphate dependent protein kinase: kinetic mechanism for the bovine skeletal muscle catalytic subunit.
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Academic Article
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Solvent isotope effects on the reaction catalyzed by yeast hexokinase.
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Academic Article
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pH studies toward the elucidation of the auxiliary catalyst for pig heart aspartate aminotransferase.
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Academic Article
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Kinetic mechanism and location of rate-determining steps for aspartase from Hafnia alvei.
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Academic Article
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Kinetic mechanism in the direction of oxidative decarboxylation for NAD-malic enzyme from Ascaris suum.
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Academic Article
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Determination of dissociation constants for enzyme-reactant complexes for NAD-malic enzyme by modulation of the thiol inactivation rate.
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Academic Article
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Use of isotope effects and pH studies to determine the chemical mechanism of Bacillus subtilis L-alanine dehydrogenase.
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Academic Article
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Metal ion activator effects on intrinsic isotope effects for hydride transfer from decarboxylation in the reaction catalyzed by the NAD-malic enzyme from Ascaris suum.
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Academic Article
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Substitution of pyridoxal 5'-phosphate in the O-acetylserine sulfhydrylase from Salmonella typhimurium by cofactor analogs provides a test of the mechanism proposed for formation of the alpha-aminoacrylate intermediate.
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Academic Article
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Secondary tritium and solvent deuterium isotope effects as a probe of the reaction catalyzed by porcine recombinant dihydropyrimidine dehydrogenase.
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Academic Article
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Cloning, expression, purification, and characterization of the 6-phosphogluconate dehydrogenase from sheep liver.
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Academic Article
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Cysteine 42 is important for maintaining an integral active site for O-acetylserine sulfhydrylase resulting in the stabilization of the alpha-aminoacrylate intermediate.
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Academic Article
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Oxidative decarboxylation of 6-phosphogluconate by 6-phosphogluconate dehydrogenase proceeds by a stepwise mechanism with NADP and APADP as oxidants.
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Academic Article
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Expression and stereochemical and isotope effect studies of active 4-oxalocrotonate decarboxylase.
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Academic Article
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O-acetylserine sulfhydrylase.
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Academic Article
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Tartrate dehydrogenase catalyzes the stepwise oxidative decarboxylation of D-malate with both NAD and thio-NAD.
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Academic Article
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Alternative substrates for malic enzyme: oxidative decarboxylation of L-aspartate.
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Academic Article
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Kinetic mechanism of NAD:malic enzyme from Ascaris suum in the direction of reductive carboxylation.
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Academic Article
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Crystallographic studies on Ascaris suum NAD-malic enzyme bound to reduced cofactor and identification of an effector site.
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Academic Article
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Ascaris suum NAD-malic enzyme is activated by L-malate and fumarate binding to separate allosteric sites.
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Academic Article
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Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.
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Academic Article
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Structure and mechanism of O-acetylserine sulfhydrylase.
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Academic Article
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Dihydropyrimidine dehydrogenase: a flavoprotein with four iron-sulfur clusters.
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Academic Article
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Multiple isotope effects with alternative dinucleotide substrates as a probe of the malic enzyme reaction.
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Academic Article
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Modification of a thiol at the active site of the Ascaris suum NAD-malic enzyme results in changes in the rate-determining steps for oxidative decarboxylation of L-malate.
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Academic Article
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Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. II. Theory.
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Academic Article
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Regulatory mechanism of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae. I. Kinetic studies.
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Academic Article
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Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate.
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Academic Article
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Importance in catalysis of the 6-phosphate-binding site of 6-phosphogluconate in sheep liver 6-phosphogluconate dehydrogenase.
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Academic Article
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An isothermal titration calorimetry study of the binding of substrates and ligands to the tartrate dehydrogenase from Pseudomonas putida reveals half-of-the-sites reactivity.
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Academic Article
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A rapid purification procedure and computer-assisted sulfide ion selective electrode assay for O-acetylserine sulfhydrylase from Salmonella typhimurium.
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Academic Article
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Isotope partitioning for NAD-malic enzyme from Ascaris suum confirms a steady-state random kinetic mechanism.
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Academic Article
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Control of ionizable residues in the catalytic mechanism of tryptophan synthase from Salmonella typhimurium.
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Academic Article
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Crystal structures of ligand-bound saccharopine dehydrogenase from Saccharomyces cerevisiae.
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Academic Article
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The relationship between glycemic control and falls in older adults.
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Academic Article
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Roles of histidines 154 and 189 and aspartate 139 in the active site of serine acetyltransferase from Haemophilus influenzae.
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Academic Article
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Evidence for a catalytic dyad in the active site of homocitrate synthase from Saccharomyces cerevisiae.
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Academic Article
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Molecular basis for the isozymes of bovine glucose-6-phosphate isomerase.
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Academic Article
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Kinetics and mechanism of benzoylformate decarboxylase using 13C and solvent deuterium isotope effects on benzoylformate and benzoylformate analogues.
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Academic Article
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Effects of osmolytes on the SLN1-YPD1-SSK1 phosphorelay system from Saccharomyces cerevisiae.
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Academic Article
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A two-step process controls the formation of the bienzyme cysteine synthase complex.
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Academic Article
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Evidence from nitrogen-15 and solvent deuterium isotope effects on the chemical mechanism of adenosine deaminase.
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Academic Article
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Evaluation of a patient navigation program.
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Academic Article
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Protonation mechanism and location of rate-determining steps for the Ascaris suum nicotinamide adenine dinucleotide-malic enzyme reaction from isotope effects and pH studies.
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Academic Article
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Kinetic and chemical mechanisms of homocitrate synthase from Thermus thermophilus.
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Academic Article
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Mechanism from isotope effects.
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Academic Article
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Modification of an arginine residue essential for the activity of NAD-malic enzyme from Ascaris suum.
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Academic Article
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Supporting role of lysine 13 and glutamate 16 in the acid-base mechanism of saccharopine dehydrogenase from Saccharomyces cerevisiae.
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Academic Article
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Fine tuning of the active site modulates specificity in the interaction of O-acetylserine sulfhydrylase isozymes with serine acetyltransferase.
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Academic Article
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The evolution of a doctor of nursing practice capstone process: programmatic revisions to improve the quality of student projects.
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Academic Article
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Primary and secondary deuterium isotope effects on equilibrium constants for enzyme-catalyzed reactions.
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Academic Article
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Use of pH studies to elucidate the catalytic mechanism of rabbit muscle creatine kinase.
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Academic Article
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Mechanistic deductions from isotope effects in multireactant enzyme mechanisms.
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Academic Article
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pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same.
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Academic Article
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pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase.
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Academic Article
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Secondary deuterium and nitrogen-15 isotope effects in enzyme-catalyzed reactions. Chemical mechanism of liver alcohol dehydrogenase.
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Academic Article
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Lanthanide pyrophosphates as substrates for the pyrophosphate-dependent phosphofructokinases from Propionibacterium freudenreichii and Phaseolus aureus: evidence for a second metal ion required for reaction.
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Academic Article
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Product binding to the alpha-carboxyl subsite results in a conformational change at the active site of O-acetylserine sulfhydrylase-A: evidence from fluorescence spectroscopy.
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Academic Article
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Stepwise versus concerted oxidative decarboxylation catalyzed by malic enzyme: a reinvestigation.
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Academic Article
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Kinetic mechanism of serine transacetylase from Salmonella typhimurium.
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Academic Article
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pH dependence of the kinetic mechanism of the adenosine 3',5'-monophosphate dependent protein kinase catalytic subunit in the direction of magnesium adenosine 5'-diphosphate phosphorylation.
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Academic Article
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Kinetic and chemical mechanisms of the sheep liver 6-phosphogluconate dehydrogenase.
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Academic Article
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Three-dimensional structure of O-acetylserine sulfhydrylase from Salmonella typhimurium.
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Academic Article
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Catalytic competence of O-acetylserine sulfhydrylase in the crystal probed by polarized absorption microspectrophotometry.
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Academic Article
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Glutamate 190 is a general acid catalyst in the 6-phosphogluconate-dehydrogenase-catalyzed reaction.
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Academic Article
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Multiple isotope effects as a probe of proton and hydride transfer in the 6-phosphogluconate dehydrogenase reaction.
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Academic Article
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Reaction mechanism of fructose-2,6-bisphosphatase. A mutation of nucleophilic catalyst, histidine 256, induces an alteration in the reaction pathway.
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Academic Article
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Crystal structure of the H256A mutant of rat testis fructose-6-phosphate,2-kinase/fructose-2,6-bisphosphatase. Fructose 6-phosphate in the active site leads to mechanisms for both mutant and wild type bisphosphatase activities.
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Academic Article
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Lysine 199 is the general acid in the NAD-malic enzyme reaction.
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Academic Article
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Identification of an allosteric anion-binding site on O-acetylserine sulfhydrylase: structure of the enzyme with chloride bound.
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Academic Article
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Detection of intermediates in reactions catalyzed by PLP-dependent enzymes: O-acetylserine sulfhydrylase and serine-glyoxalate aminotransferase.
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Academic Article
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Characterization of the S272A,D site-directed mutations of O-acetylserine sulfhydrylase: involvement of the pyridine ring in the alpha,beta-elimination reaction.
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Academic Article
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Chemical mechanism of the serine acetyltransferase from Haemophilus influenzae.
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Academic Article
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The serine acetyltransferase reaction: acetyl transfer from an acylpantothenyl donor to an alcohol.
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Academic Article
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Interaction of serine acetyltransferase with O-acetylserine sulfhydrylase active site: evidence from fluorescence spectroscopy.
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Academic Article
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Crystal structure of the his-tagged saccharopine reductase from Saccharomyces cerevisiae at 1.7-A resolution.
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Academic Article
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The alpha-aminoadipate pathway for lysine biosynthesis in fungi.
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Academic Article
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The 2'-phosphate of NADP is responsible for proper orientation of the nicotinamide ring in the oxidative decarboxylation reaction catalyzed by sheep liver 6-phosphogluconate dehydrogenase.
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Academic Article
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Multiple roles of arginine 181 in binding and catalysis in the NAD-malic enzyme from Ascaris suum.
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Academic Article
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Proper orientation of the nicotinamide ring of NADP is important for the precatalytic conformational change in the 6-phosphogluconate dehydrogenase reaction.
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Academic Article
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Role of residues in the adenosine binding site of NAD of the Ascaris suum malic enzyme.
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Academic Article
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A novel, species-specific class of uncompetitive inhibitors of gamma-glutamyl transpeptidase.
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Academic Article
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Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum.
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Academic Article
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A lysine-tyrosine pair carries out acid-base chemistry in the metal ion-dependent pyridine dinucleotide-linked beta-hydroxyacid oxidative decarboxylases.
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Academic Article
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Introduction to the special issue. Foreword.
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Academic Article
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para-Nitrophenyl sulfate activation of human sulfotransferase 1A1 is consistent with intercepting the E[middle dot]PAP complex and reformation of E[middle dot]PAPS.
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Academic Article
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Exploring O-acetylserine sulfhydrylase-B isoenzyme from Salmonella typhimurium by fluorescence spectroscopy.
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Academic Article
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Kinetic studies of the yeast His-Asp phosphorelay signaling pathway.
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Academic Article
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(31)P NMR spectroscopy senses the microenvironment of the 5'-phosphate group of enzyme-bound pyridoxal 5'-phosphate.
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Academic Article
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Gamma-glutamyl compounds: substrate specificity of gamma-glutamyl transpeptidase enzymes.
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Academic Article
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Cardiovascular risk assessment for persons living with HIV.
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Academic Article
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The oxidation state of active site thiols determines activity of saccharopine dehydrogenase at low pH.
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Academic Article
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Contribution of K99 and D319 to substrate binding and catalysis in the saccharopine dehydrogenase reaction.
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Academic Article
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Divergent effects of compounds on the hydrolysis and transpeptidation reactions of ?-glutamyl transpeptidase.
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Academic Article
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Structure of 6-diazo-5-oxo-norleucine-bound human gamma-glutamyl transpeptidase 1, a novel mechanism of inactivation.
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Academic Article
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Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis.
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Academic Article
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salmonella typhimurium/enzymol.
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Academic Article
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Cysteine synthetase from Salmonella typhimurium LT-2. Aggregation, kinetic behavior, and effect of modifiers.
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Academic Article
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A reaction mechanism from steady state kinetic studies for O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2.
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Academic Article
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Overall mechanism and rate equation for O-acetylserine sulfhydrylase.
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Academic Article
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Kinetic mechanism of dihydropyrimidine dehydrogenase from pig liver.
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Academic Article
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pH dependence of kinetic parameters for oxalacetate decarboxylation and pyruvate reduction reactions catalyzed by malic enzyme.
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Academic Article
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The pH dependence of the reductive carboxylation of pyruvate by malic enzyme.
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Academic Article
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Diethylpyrocarbonate inactivation of NAD-malic enzyme from Ascaris suum.
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Academic Article
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Equilibrium model in an in vitro poly(ADP-ribose) turnover system.
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Academic Article
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Identification and spectral characterization of the external aldimine of the O-acetylserine sulfhydrylase reaction.
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Academic Article
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Acid-base chemical mechanism of O-acetylserine sulfhydrylases-A and -B from pH studies.
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Academic Article
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A pH-dependent allosteric transition in Ascaris suum phosphofructokinase distinct from that observed with fructose 2,6-bisphosphate.
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Academic Article
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The 2'-phosphate of NADP is critical for optimum productive binding to 6-phosphogluconate dehydrogenase from Candida utilis.
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Academic Article
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Cloning and nucleotide sequence of a full-length cDNA encoding Ascaris suum malic enzyme.
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Academic Article
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Acid base catalytic mechanism of the dihydropyrimidine dehydrogenase from pH studies.
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Academic Article
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Product dependence of deuterium isotope effects in enzyme-catalyzed reactions.
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Academic Article
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Overall kinetic mechanism of 6-phosphogluconate dehydrogenase from Candida utilis.
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Academic Article
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Chemical mechanism of 6-phosphogluconate dehydrogenase from Candida utilis from pH studies.
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Academic Article
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Crystallization and preliminary X-ray data for the A-isozyme of O-acetylserine sulfhydrylase from Salmonella typhimurium.
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Academic Article
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Kinetic mechanisms of the A and B isozymes of O-acetylserine sulfhydrylase from Salmonella typhimurium LT-2 using the natural and alternative reactants.
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Academic Article
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Chemical mechanism of the fructose-6-phosphate,2-kinase reaction from the pH dependence of kinetic parameters of site-directed mutants of active site basic residues.
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Grant
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STRUCTURE AND MECHANISM OF NAD-MALIC ENZYME
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Grant
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STRUCTURE/MECHANISM OF 6-PHOSPHOGLUCONATE DEHYDROGENASE
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