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Janknecht, Ralf

One or more keywords matched the following properties of Janknecht, Ralf

Property	Value
phone	405/271-8001 ext 47420

One or more keywords matched the following items that are connected to Janknecht, Ralf

Item Type	Name
Concept	Transcriptional Regulator ERG
Concept	Human Embryonic Stem Cells
Concept	Mouse Embryonic Stem Cells
Concept	Extracellular Vesicles
Concept	Kelch-Like ECH-Associated Protein 1
Concept	Protein Domains
Concept	rab27 GTP-Binding Proteins
Concept	Antineoplastic Agents
Concept	Amino Acid Sequence
Concept	Cyclic AMP
Concept	B-Lymphocytes
Concept	Blood Vessels
Concept	Base Sequence
Concept	Bromodeoxyuridine
Concept	Cell Adhesion
Concept	Cell Line
Concept	Cell Line, Transformed
Concept	Cell Nucleolus
Concept	Cell Nucleus
Concept	Cytomegalovirus
Concept	Chromatin
Concept	Chromosomes
Concept	Chromosomes, Human, Pair 12
Concept	Chromosomes, Human, Pair 16
Concept	Chromosomes, Human, Pair 21
Concept	Citric Acid Cycle
Concept	Diabetes Mellitus, Type 2
Concept	Diabetic Angiopathies
Concept	Exons
Concept	Exoribonucleases
Concept	Extracellular Matrix
Concept	Cysteine Endopeptidases
Concept	Collagen
Concept	Colonic Neoplasms
Concept	Endothelium, Vascular
Concept	Enhancer Elements, Genetic
Concept	Fatty Acids, Monounsaturated
Concept	Enzyme Induction
Concept	Doxorubicin
Concept	Drosophila
Concept	Drosophila melanogaster
Concept	Escherichia coli
Concept	Carcinoma, Hepatocellular
Concept	Ecdysone
Concept	Herpesviridae
Concept	Heterochromatin
Concept	Histone Deacetylases
Concept	Embryo, Mammalian
Concept	HeLa Cells
Concept	Glial Fibrillary Acidic Protein
Concept	Karyotyping
Concept	Lithium
Concept	Ketoglutaric Acids
Concept	Glutathione Transferase
Concept	Lymphocytes
Concept	Lymphokines
Concept	Insulin
Concept	Insulin-Like Growth Factor I
Concept	Nitrobenzoates
Concept	Introns
Concept	N-Glycosyl Hydrolases
Concept	Nucleosomes
Concept	Microtubules
Concept	Mitochondria
Concept	Molecular Sequence Data
Concept	Phosphoprotein Phosphatases
Concept	Precipitin Tests
Concept	Repressor Proteins
Concept	Oryza
Concept	Endopeptidases
Concept	RNA Polymerase II
Concept	T-Lymphocytes
Concept	Temperature
Concept	Testicular Neoplasms
Concept	Transcription, Genetic
Concept	Protein Biosynthesis
Concept	Translocation, Genetic
Concept	Human T-lymphotropic virus 1
Concept	Endosomes
Concept	Trans-Activators
Concept	Zebrafish
Concept	Blotting, Western
Concept	Antigens, CD
Concept	Colorectal Neoplasms
Concept	Electrophoresis, Gel, Two-Dimensional
Concept	Diffusion Chambers, Culture
Concept	Cell Adhesion Molecules
Concept	Proto-Oncogene Proteins c-jun
Concept	Proto-Oncogene Proteins c-fos
Concept	Succinate Dehydrogenase
Concept	Genes, fos
Concept	Endometrial Neoplasms
Concept	Vaccinia virus
Concept	Cyclic AMP Response Element-Binding Protein
Concept	Sequence Homology, Amino Acid
Concept	In Situ Hybridization
Concept	In Situ Hybridization, Fluorescence
Concept	Prostate-Specific Antigen
Concept	Adenovirus E1A Proteins
Concept	Transcription Factor AP-1
Concept	Hair Follicle
Concept	Isochromosomes
Concept	Disease Progression
Concept	Antigens, CD19
Concept	Sp1 Transcription Factor
Concept	ras Proteins
Concept	Proto-Oncogene Proteins c-kit
Concept	Prostatic Intraepithelial Neoplasia
Concept	Cell Lineage
Concept	HT29 Cells
Concept	TATA Box
Concept	Genes, erbB-2
Concept	Fluorescent Antibody Technique, Indirect
Concept	3T3 Cells
Concept	DNA Methylation
Concept	GTP-Binding Proteins
Concept	Angiogenesis Inhibitors
Concept	Proto-Oncogene Proteins c-myb
Concept	rap GTP-Binding Proteins
Concept	rab GTP-Binding Proteins
Concept	Myogenic Regulatory Factors
Concept	rab5 GTP-Binding Proteins
Concept	DNA, Complementary
Concept	rho GTP-Binding Proteins
Concept	Matrix Metalloproteinase 1
Concept	Matrix Metalloproteinase 7
Concept	Amino Acid Motifs
Concept	T-Box Domain Proteins
Concept	Crystallography, X-Ray
Concept	Succinic Acid
Concept	Proto-Oncogene Proteins c-raf
Concept	Cyclin D1
Concept	Cyclin-Dependent Kinase 9
Concept	Promoter Regions, Genetic
Concept	5' Flanking Region
Concept	3' Flanking Region
Concept	E-Box Elements
Concept	Prostatic Neoplasms
Concept	Small Ubiquitin-Related Modifier Proteins
Concept	Serum Response Factor
Concept	Polyadenylation
Concept	Basic-Leucine Zipper Transcription Factors
Concept	beta Catenin
Concept	NF-E2-Related Factor 2
Concept	Focal Adhesion Protein-Tyrosine Kinases
Concept	Activating Transcription Factor 2
Concept	Genome-Wide Association Study
Concept	Tumor Cells, Cultured
Concept	Exosomes
Concept	Bone Morphogenetic Protein 2
Concept	Bone Morphogenetic Protein 4
Concept	Interleukin-6
Concept	Gene Expression
Concept	RNA Interference
Concept	Transcription Factor TFIID
Concept	Tumor Suppressor Protein p53
Concept	Hepacivirus
Concept	Cytokines
Concept	Transforming Growth Factor beta
Concept	Cyclins
Concept	Proto-Oncogene Proteins c-myc
Concept	Laser Scanning Cytometry
Concept	Mitogen-Activated Protein Kinase 3
Concept	MAP Kinase Kinase 6
Concept	MAP Kinase Kinase 4
Concept	Adaptor Proteins, Signal Transducing
Concept	14-3-3 Proteins
Concept	Cell Proliferation
Concept	Green Fluorescent Proteins
Concept	Genes, Immediate-Early
Concept	DEAD-box RNA Helicases
Concept	Vascular Endothelial Growth Factor Receptor-2
Concept	Cyclic AMP-Dependent Protein Kinases
Concept	Leukemia Inhibitory Factor
Concept	Genes, Reporter
Concept	DNA Primers
Concept	Microdissection
Concept	Vascular Endothelial Growth Factor A
Concept	Dimerization
Concept	Computational Biology
Concept	Transforming Growth Factor beta1
Concept	Bone Morphogenetic Proteins
Concept	Nuclear Receptor Coactivator 3
Concept	ARNTL Transcription Factors
Concept	Cryptochromes
Concept	COS Cells
Concept	Cyclin-Dependent Kinase Inhibitor p21
Concept	Proto-Oncogene Proteins c-ets
Concept	Proto-Oncogene Protein c-ets-2
Concept	STAT3 Transcription Factor
Concept	ets-Domain Protein Elk-1
Concept	ets-Domain Protein Elk-4
Concept	Gene Silencing
Concept	CREB-Binding Protein
Concept	HEK293 Cells
Concept	Epigenomics
Concept	Mitogen-Activated Protein Kinase Kinases
Concept	Protein Interaction Domains and Motifs
Concept	Transcription Initiation Site
Concept	Mesenchymal Stem Cell Transplantation
Concept	HCT116 Cells
Concept	Cell Line, Tumor
Concept	Membrane Potential, Mitochondrial
Concept	Proteasome Endopeptidase Complex
Concept	Upstream Stimulatory Factors
Concept	Kruppel-Like Transcription Factors
Concept	Early Growth Response Transcription Factors
Concept	Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Concept	Smad Proteins
Concept	Proto-Oncogene Protein c-fli-1
Concept	SOX9 Transcription Factor
Concept	Forkhead Transcription Factors
Concept	Sex-Determining Region Y Protein
Concept	Smad1 Protein
Concept	Smad2 Protein
Concept	Smad3 Protein
Concept	Smad4 Protein
Concept	Smad7 Protein
Concept	Nuclear Receptor Coactivator 2
Concept	Molecular Dynamics Simulation
Concept	Histone Deacetylase 1
Concept	Histone Deacetylase 2
Concept	Molecular Docking Simulation
Concept	Transcription Factor 4
Concept	Cells, Cultured
Concept	Chickens
Concept	Docosahexaenoic Acids
Concept	Flow Cytometry
Concept	Fluorescent Antibody Technique
Concept	Immunohistochemistry
Academic Article	Elevated circulation levels of an antiangiogenic SERPIN in patients with diabetic microvascular complications impair wound healing through suppression of Wnt signaling.
Academic Article	Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1.
Academic Article	HuR Reduces Radiation-Induced DNA Damage by Enhancing Expression of ARID1A.
Academic Article	Fluvastatin interferes with hepatitis C virus replication via microtubule bundling and a doublecortin-like kinase-mediated mechanism.
Academic Article	Nuclear fusion of signaling pathways.
Academic Article	The versatile functions of the transcriptional coactivators p300 and CBP and their roles in disease.
Academic Article	Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300.
Academic Article	Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1).
Academic Article	Overexpression of the TGF-beta antagonist Smad7 in endometrial cancer.
Academic Article	Activation of androgen receptor by histone demethylases JMJD2A and JMJD2D.
Academic Article	Synthesis and activity of N-oxalylglycine and its derivatives as Jumonji C-domain-containing histone lysine demethylase inhibitors.
Academic Article	Independence of repressive histone marks and chromatin compaction during senescent heterochromatic layer formation.
Academic Article	KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells.
Academic Article	Pro-growth role of the JMJD2C histone demethylase in HCT-116 colon cancer cells and identification of curcuminoids as JMJD2 inhibitors.
Academic Article	Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.
Academic Article	ETS transcription factor ERG cooperates with histone demethylase KDM4A.
Academic Article	Upregulation of PSMD10 caused by the JMJD2A histone demethylase.
Academic Article	Cooperation between ETS variant 2 and Jumonji domain-containing 2 histone demethylases.
Academic Article	Relationship between ETS Transcription Factor ETV1 and TGF-ß-regulated SMAD Proteins in Prostate Cancer.
Academic Article	Opposite Roles of the JMJD1A Interaction Partners MDFI and MDFIC in Colorectal Cancer.
Academic Article	Characterization of a putative transcription factor gene expressed in the 20-OH-ecdysone inducible puff 74EF in Drosophila melanogaster.
Academic Article	High affinity DNA binding of native full length c-Myb and differential proteolytic sensitivity of its N- and C-terminal domains.
Academic Article	Quantitative structure-activity analysis correlating Ras/Raf interaction in vitro to Raf activation in vivo.
Academic Article	Interaction of the co-activator CBP with Myb proteins: effects on Myb-specific transactivation and on the cooperativity with NF-M.
Academic Article	Role of focal adhesion kinase in MAP kinase activation by insulin-like growth factor-I or insulin.
Academic Article	The Ewing's sarcoma gene product functions as a transcriptional activator.
Academic Article	Modulation of transforming growth factor beta (TGFbeta)/Smad transcriptional responses through targeted degradation of TGFbeta-inducible early gene-1 by human seven in absentia homologue.
Academic Article	Functional analysis of the transcription factor ER71 and its activation of the matrix metalloproteinase-1 promoter.
Academic Article	Regulation of Her2/neu promoter activity by the ETS transcription factor, ER81.
Academic Article	TGFbeta inducible early gene enhances TGFbeta/Smad-dependent transcriptional responses.
Academic Article	Upregulation of the Catalytic Telomerase Subunit by the Transcription Factor ER81 and Oncogenic HER2/Neu, Ras, or Raf.
Academic Article	Concerted activation of ETS protein ER81 by p160 coactivators, the acetyltransferase p300 and the receptor tyrosine kinase HER2/Neu.
Academic Article	hTERT Is highly expressed in Ewing's sarcoma and activated by EWS-ETS oncoproteins.
Academic Article	Cloning of the murine ER71 gene (Etsrp71) and initial characterization of its promoter.
Academic Article	EWS-ETS oncoproteins: the linchpins of Ewing tumors.
Academic Article	Repression of transcription by TSGA/Jmjd1a, a novel interaction partner of the ETS protein ER71.
Academic Article	Diversity within the JMJD2 histone demethylase family.
Academic Article	Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF.
Academic Article	Involvement of RNA helicases p68 and p72 in colon cancer.
Academic Article	ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification.
Academic Article	Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.
Academic Article	Multi-talented DEAD-box proteins and potential tumor promoters: p68 RNA helicase (DDX5) and its paralog, p72 RNA helicase (DDX17).
Academic Article	Phosphorylated c-Jun and Fra-1 induce matrix metalloproteinase-1 and thereby regulate invasion activity of 143B osteosarcoma cells.
Academic Article	Histone demethylase JMJD5 is essential for embryonic development.
Academic Article	ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.
Academic Article	Oncogenic features of the JMJD2A histone demethylase in breast cancer.
Academic Article	Developmental localization of nephrin in zebrafish and medaka pronephric glomerulus.
Academic Article	Transgenic expression of a canonical Wnt inhibitor, kallistatin, is associated with decreased circulating CD19+ B lymphocytes in the peripheral blood.
Academic Article	A potential common role of the Jumonji C domain-containing 1A histone demethylase and chromatin remodeler ATRX in promoting colon cancer.
Academic Article	Multifunctional APJ Pathway Promotes Ovarian Cancer Progression and Metastasis.
Academic Article	Extracellular vesicles from human bone marrow mesenchymal stem cells repair organ damage caused by cadmium poisoning in a medaka model.
Academic Article	Elk-1 protein domains required for direct and SRF-assisted DNA-binding.
Academic Article	(HX)n repeats: a pH-controlled protein-protein interaction motif of eukaryotic transcription factors?
Academic Article	Co-occurrence of CArG boxes and TCF sites within viral genomes.
Academic Article	Heterogeneity of ternary complex factors in HeLa cell nuclear extracts.
Academic Article	Transcription. A growing coactivator network.
Academic Article	MAP kinase-dependent transcriptional coactivation by Elk-1 and its cofactor CBP.
Academic Article	TGF-beta-stimulated cooperation of smad proteins with the coactivators CBP/p300.
Academic Article	CBP/p300 interact with and function as transcriptional coactivators of BRCA1.
Academic Article	Activation of Smad1-mediated transcription by p300/CBP.
Academic Article	Rapid and efficient purification of native histidine-tagged protein expressed by recombinant vaccinia virus.
Academic Article	Cell type-specific inhibition of the ETS transcription factor ER81 by mitogen-activated protein kinase-activated protein kinase 2.
Academic Article	HER2/Neu-mediated activation of the ETS transcription factor ER81 and its target gene MMP-1.
Academic Article	Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A.
Academic Article	Transcriptional regulation of Smad2 is required for enhancement of TGFbeta/Smad signaling by TGFbeta inducible early gene.
Academic Article	Acetylation-mediated transcriptional activation of the ETS protein ER81 by p300, P/CAF, and HER2/Neu.
Academic Article	HER2/Neu- and TAK1-mediated up-regulation of the transforming growth factor beta inhibitor Smad7 via the ETS protein ER81.
Academic Article	Vascular endothelial growth factor expression is up-regulated by EWS-ETS oncoproteins and Sp1 and may represent an independent predictor of survival in Ewing's sarcoma.
Academic Article	Succinate inhibition of alpha-ketoglutarate-dependent enzymes in a yeast model of paraganglioma.
Academic Article	Pleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.
Academic Article	The JMJD2A demethylase regulates apoptosis and proliferation in colon cancer cells.
Academic Article	Regulation of tumor suppressor p53 and HCT116 cell physiology by histone demethylase JMJD2D/KDM4D.
Academic Article	14-3-3 proteins modulate the ETS transcription factor ETV1 in prostate cancer.
Academic Article	Distinct biochemical and functional properties of two Rab5 homologs from the rice blast fungus Magnaporthe oryzae.
Academic Article	Exosome-mediated microRNA signaling from breast cancer cells is altered by the anti-angiogenesis agent docosahexaenoic acid (DHA).
Academic Article	Regulation of the DNA Methylation Landscape in Human Somatic Cell Reprogramming by the miR-29 Family.
Academic Article	JMJD5 links CRY1 function and proteasomal degradation.
Academic Article	Regulatory squelching.
Academic Article	Correction: JMJD5 links CRY1 function and proteasomal degradation.
Academic Article	Crucial Functions of the JMJD1/KDM3 Epigenetic Regulators in Cancer.
Academic Article	Gene regulation by Ets proteins.
Academic Article	Activation of the Sap-1a transcription factor by the c-Jun N-terminal kinase (JNK) mitogen-activated protein kinase.
Academic Article	Phosphorylation of ETS transcription factor ER81 in a complex with its coactivators CREB-binding protein and p300.
Academic Article	Regulation of telomerase reverse transcriptase gene activity by upstream stimulatory factor.
Academic Article	Upregulation of the matrix metalloproteinase-1 gene by the Ewing's sarcoma associated EWS-ER81 and EWS-Fli-1 oncoproteins, c-Jun and p300.
Academic Article	On the road to immortality: hTERT upregulation in cancer cells.
Academic Article	Repression of Smad3 activity by histone demethylase SMCX/JARID1C.
Academic Article	Rcl is a novel ETV1/ER81 target gene upregulated in breast tumors.
Academic Article	Induction of prostatic intraepithelial neoplasia and modulation of androgen receptor by ETS variant 1/ETS-related protein 81.
Academic Article	Histone demethylase JARID1B/KDM5B is a corepressor of TIEG1/KLF10.
Academic Article	Transcription factors ER71/ETV2 and SOX9 participate in a positive feedback loop in fetal and adult mouse testis.
Academic Article	ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.
Academic Article	Nephrin and Podocin functions are highly conserved between the zebrafish pronephros and mammalian metanephros.
Academic Article	Stimulation of ß-catenin and colon cancer cell growth by the KDM4B histone demethylase.
Academic Article	A PGAM5-KEAP1-Nrf2 complex is required for stress-induced mitochondrial retrograde trafficking.
Academic Article	Clipping of arginine-methylated histone tails by JMJD5 and JMJD7.
Academic Article	YAP1 inhibition radiosensitizes triple negative breast cancer cells by targeting the DNA damage response and cell survival pathways.
Academic Article	The small members of the JMJD protein family: Enzymatic jewels or jinxes?
Academic Article	JMJD5 couples with CDK9 to release the paused RNA polymerase II.
Academic Article	Cooperation between ETS transcription factor ETV1 and histone demethylase JMJD1A in colorectal cancer.
Academic Article	C-terminal phosphorylation of the serum-response factor.
Academic Article	Regulation of the c-fos promoter.
Academic Article	p38-2, a novel mitogen-activated protein kinase with distinct properties.
Academic Article	Sumoylation of transcription factor ETV1 modulates its oncogenic potential in prostate cancer.
Academic Article	Promotion of colorectal cancer by transcription factor BHLHE40 involves upregulation of ADAM19 and KLF7.
Academic Article	Absence of either Ripk3 or Mlkl reduces incidence of hepatocellular carcinoma independent of liver fibrosis.
Academic Article	SET7/9-mediated methylation affects oncogenic functions of histone demethylase JMJD2A.
Academic Article	Methylation of the epigenetic JMJD2D protein by SET7/9 promotes prostate tumorigenesis.
Academic Article	Methylation of the JMJD2B epigenetic regulator differentially affects its ability to coactivate the ETV1 and JUN transcription factors.

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