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Chromosomes, Human, Pair 1
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Chromosomes, Human, Pair 10
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Concept
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Chromosomes, Human, Pair 11
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Chromosomes, Human, Pair 16
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Chromosomes, Human, Pair 18
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Chromosomes, Human, Pair 19
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Chromosomes, Human, Pair 2
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Chromosomes, Human, Pair 3
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Chromosomes, Human, Pair 4
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Chromosomes, Human, Pair 5
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Chromosomes, Human, Pair 6
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Chromosomes, Human, Pair 8
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Herpesvirus 4, Human
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Humans
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Concept
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Influenza, Human
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Concept
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Herpesvirus 3, Human
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Herpesvirus 2, Human
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Herpesvirus 1, Human
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Genome, Human
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Chromosomes, Human, X
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Chromosomes, Human, Y
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Academic Article
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Anthrax vaccination induced anti-lethal factor IgG: fine specificity and neutralizing capacity.
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Academic Article
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Influenza vaccination responses in human systemic lupus erythematosus: impact of clinical and demographic features.
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Academic Article
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Individual antibody and T cell responses to vaccination and infection with the 2009 pandemic swine-origin H1N1 influenza virus.
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Academic Article
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Influenza vaccination can induce new-onset anticardiolipins but not ß2-glycoprotein-I antibodies among patients with systemic lupus erythematosus.
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Academic Article
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Influenza A (H1N1) virus infection triggers severe pulmonary inflammation in lupus-prone mice following viral clearance.
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Academic Article
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Antibodies to periodontogenic bacteria are associated with higher disease activity in lupus patients.
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Academic Article
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Mock Recruitment for the Study of Antimalarials in an Incomplete Lupus Erythematosus Trial.
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Academic Article
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Study of Anti-Malarials in Incomplete Lupus Erythematosus (SMILE): study protocol for a randomized controlled trial.
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Academic Article
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Insights From Analysis of Human Antigen-Specific Memory B Cell Repertoires.
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Academic Article
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Prognostic significance of repeat biopsy in lupus nephritis: Histopathologic worsening and a short time between biopsies is associated with significantly increased risk for end stage renal disease and death.
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Academic Article
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Immunodominance of antigenic site B over site A of hemagglutinin of recent H3N2 influenza viruses.
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Academic Article
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Lupus patient decisions about clinical trial participation: a qualitative evaluation of perceptions, facilitators and barriers.
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Academic Article
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Toxin-neutralizing antibodies elicited by naturally acquired cutaneous anthrax are elevated following severe disease and appear to target conformational epitopes.
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Academic Article
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Cell-bound complement activation products associate with lupus severity in SLE.
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Academic Article
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Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype.
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Academic Article
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The sepsis model: an emerging hypothesis for the lethality of inhalation anthrax.
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Academic Article
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Antibody quantity versus quality after influenza vaccination.
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Academic Article
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Select human anthrax protective antigen epitope-specific antibodies provide protection from lethal toxin challenge.
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Academic Article
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Assessment of Translational and Interdisciplinary Clinical Research at an Oklahoma Health Sciences Center.
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Academic Article
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Memory B Cells Encode Neutralizing Antibody Specific for Toxin B from the Clostridium difficile Strains VPI 10463 and NAP1/BI/027 but with Superior Neutralization of VPI 10463 Toxin B.
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Academic Article
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Anthrax Vaccine Precipitated Induces Edema Toxin-Neutralizing, Edema Factor-Specific Antibodies in Human Recipients.
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Academic Article
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Human C. difficile toxin-specific memory B cell repertoires encode poorly neutralizing antibodies.
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Academic Article
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Brief Report: Patients With Primary Sjögren's Syndrome Who Are Positive for Autoantibodies to Tripartite Motif-Containing Protein 38 Show Greater Disease Severity.
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Academic Article
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Epstein Barr virus nuclear antigen 1 (EBNA-1) peptides recognized by adult multiple sclerosis patient sera induce neurologic symptoms in a murine model.
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Academic Article
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Immunization of mice with human 60-kd Ro peptides results in epitope spreading if the peptides are highly homologous between human and mouse.
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Academic Article
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Rapid clinical progression to diagnosis among African-American men with systemic lupus erythematosus.
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Academic Article
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Development of autoantibodies before the clinical onset of systemic lupus erythematosus.
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Academic Article
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Early events in lupus humoral autoimmunity suggest initiation through molecular mimicry.
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Academic Article
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Humoral antigenic targets of the ribosomal P0 lupus autoantigen are not limited to the carboxyl region.
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Academic Article
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Epstein-Barr virus and molecular mimicry in systemic lupus erythematosus.
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Academic Article
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Overlapping features of thrombotic thrombocytopenic purpura and systemic lupus erythematosus.
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Academic Article
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Clinical criteria for systemic lupus erythematosus precede diagnosis, and associated autoantibodies are present before clinical symptoms.
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Academic Article
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Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans.
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Academic Article
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Common variants within MECP2 confer risk of systemic lupus erythematosus.
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Academic Article
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Osteopontin and systemic lupus erythematosus association: a probable gene-gender interaction.
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Academic Article
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Lupus-like autoantibody development in rabbits and mice after immunization with EBNA-1 fragments.
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Academic Article
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Patients with familial and sporadic onset SLE have similar clinical profiles but vary profoundly by race.
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Academic Article
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Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus.
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Academic Article
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High-density genotyping of STAT4 reveals multiple haplotypic associations with systemic lupus erythematosus in different racial groups.
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Academic Article
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Replication of the BANK1 genetic association with systemic lupus erythematosus in a European-derived population.
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Academic Article
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Genetic associations of LYN with systemic lupus erythematosus.
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Academic Article
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Male-only systemic lupus.
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Academic Article
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Polymorphisms in the Hsp70 gene locus are genetically associated with systemic lupus erythematosus.
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Academic Article
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Anti-neutrophil cytoplasmic antibodies target sequential functional proteinase 3 epitopes in the sera of patients with Wegener’s granulomatosis.
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Academic Article
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Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus.
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Academic Article
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Anti-peptidoglycan antibodies and Fc? receptors are the key mediators of inflammation in Gram-positive sepsis.
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Academic Article
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Antibody response to common viruses and human leukocyte antigen-DRB1 in pediatric multiple sclerosis.
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Academic Article
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Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis.
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Academic Article
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Variable association of reactive intermediate genes with systemic lupus erythematosus in populations with different African ancestry.
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Academic Article
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Herpes zoster vaccination in SLE: a pilot study of immunogenicity.
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Academic Article
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Implications of a vasodilatory human monoclonal autoantibody in postural hypotension.
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Academic Article
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Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren's syndrome.
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Academic Article
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Preferential binding to Elk-1 by SLE-associated IL10 risk allele upregulates IL10 expression.
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Academic Article
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End-stage renal disease in African Americans with lupus nephritis is associated with APOL1.
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Academic Article
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Autoimmune hepatitis in the Alaska Native population: autoantibody profile and HLA associations.
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Academic Article
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Protective environmental factors for neuromyelitis optica.
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Academic Article
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High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.
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Academic Article
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Genetic associations of leptin-related polymorphisms with systemic lupus erythematosus.
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Academic Article
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X Chromosome Dose and Sex Bias in Autoimmune Diseases: Increased Prevalence of 47,XXX in Systemic Lupus Erythematosus and Sjögren's Syndrome.
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Academic Article
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Genome-Wide DNA Methylation Study Identifies Significant Epigenomic Changes in Osteoarthritic Subchondral Bone and Similarity to Overlying Cartilage.
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Academic Article
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Decreased SMG7 expression associates with lupus-risk variants and elevated antinuclear antibody production.
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Academic Article
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Antigen nature and complexity influence human antibody light chain usage and specificity.
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Academic Article
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Impact of heart rate variability, a marker for cardiac health, on lupus disease activity.
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Academic Article
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Clinical and Serologic Features in Patients With Incomplete Lupus Classification Versus Systemic Lupus Erythematosus Patients and Controls.
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Academic Article
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Pathways of impending disease flare in African-American systemic lupus erythematosus patients.
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Academic Article
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Lethal factor antibodies contribute to lethal toxin neutralization in recipients of anthrax vaccine precipitated.
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Academic Article
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ARID3a gene profiles are strongly associated with human interferon alpha production.
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Academic Article
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Novel genetic associations with interferon in systemic lupus erythematosus identified by replication and fine-mapping of trait-stratified genome-wide screen.
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Academic Article
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Top-down Mass Spectrometry Analysis of Human Serum Autoantibody Antigen-Binding Fragments.
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Academic Article
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Immunologic findings precede rapid lupus flare after transient steroid therapy.
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Academic Article
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Association of Epstein-Barr virus serological reactivation with transitioning to systemic lupus erythematosus in at-risk individuals.
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Academic Article
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Associations between daily alcohol consumption and systemic lupus erythematosus-related cytokines and chemokines among US female nurses without SLE.
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Academic Article
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ARID3a expression in human hematopoietic stem cells is associated with distinct gene patterns in aged individuals.
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Academic Article
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Genetic Association of a Gain-of-Function IFNGR1 Polymorphism and the Intergenic Region LNCAROD/DKK1 With Behçet's Disease.
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Academic Article
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Linear epitope mapping of an Sm B/B' polypeptide.
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Academic Article
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Human lupus anti-spliceosome A protein autoantibodies bind contiguous surface structures and segregate into two sequential epitope binding patterns.
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Academic Article
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Visualization of P-selectin glycoprotein ligand-1 as a highly extended molecule and mapping of protein epitopes for monoclonal antibodies.
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Academic Article
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An increased prevalence of Epstein-Barr virus infection in young patients suggests a possible etiology for systemic lupus erythematosus.
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Academic Article
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Shared early autoantibody recognition events in the development of anti-Sm B/B' in human lupus.
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Academic Article
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Systemic lupus erythematosus in adults is associated with previous Epstein-Barr virus exposure.
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Academic Article
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Infectious mononucleosis patients temporarily recognize a unique, cross-reactive epitope of Epstein-Barr virus nuclear antigen-1.
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Academic Article
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Peptide mimics of a major lupus epitope of SmB/B'.
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Academic Article
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Anti-Ro and anti-nRNP response in unaffected family members of SLE patients.
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Academic Article
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Modification of lupus-associated 60-kDa Ro protein with the lipid oxidation product 4-hydroxy-2-nonenal increases antigenicity and facilitates epitope spreading.
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Academic Article
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Update in rheumatoid arthritis therapy.
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Academic Article
|
Epstein-Barr virus infection induces lupus autoimmunity.
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Academic Article
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The curiously suspicious: a role for Epstein-Barr virus in lupus.
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Academic Article
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Fine specificity mapping of autoantigens targeted by anti-centromere autoantibodies.
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Academic Article
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Hydroxychloroquine sulfate treatment is associated with later onset of systemic lupus erythematosus.
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Academic Article
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Primary Sjogren's syndrome: current and prospective therapies.
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Academic Article
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Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
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Academic Article
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Autoantibody prevalence and lupus characteristics in a unique African American population.
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Academic Article
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Key developmental transitions in human germinal center B cells are revealed by differential CD45RB expression.
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Academic Article
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Evaluation of C1q genomic region in minority racial groups of lupus.
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Academic Article
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ITGAM coding variant (rs1143679) influences the risk of renal disease, discoid rash and immunological manifestations in patients with systemic lupus erythematosus with European ancestry.
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Academic Article
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Differential expression of immunomodulatory galectin-1 in peripheral leukocytes and adult tissues and its cytosolic organization in striated muscle.
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Academic Article
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Network analysis of associations between serum interferon-a activity, autoantibodies, and clinical features in systemic lupus erythematosus.
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Academic Article
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Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
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Academic Article
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Vitamin D status and antibody levels to common viruses in pediatric-onset multiple sclerosis.
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Academic Article
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Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus.
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Academic Article
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Association of PPP2CA polymorphisms with systemic lupus erythematosus susceptibility in multiple ethnic groups.
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Academic Article
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Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.
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Academic Article
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Genetic and physical interaction of the B-cell systemic lupus erythematosus-associated genes BANK1 and BLK.
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Academic Article
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Human monoclonal antibodies generated following vaccination with AVA provide neutralization by blocking furin cleavage but not by preventing oligomerization.
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Academic Article
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Association of two independent functional risk haplotypes in TNIP1 with systemic lupus erythematosus.
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Academic Article
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Impact of genetic ancestry and sociodemographic status on the clinical expression of systemic lupus erythematosus in American Indian-European populations.
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Academic Article
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Rheumatic disease among Oklahoma tribal populations: a cross-sectional study.
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Academic Article
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Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups.
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Academic Article
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Editorial for Lindop et al. "long-term Ro60 humoral autoimmunity in primary Sjögren's syndrome is maintained by rapid clonal turnover".
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Academic Article
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Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.
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Academic Article
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Familial aggregation of high tumor necrosis factor alpha levels in systemic lupus erythematosus.
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Academic Article
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Proinflammatory adaptive cytokine and shed tumor necrosis factor receptor levels are elevated preceding systemic lupus erythematosus disease flare.
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Academic Article
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Genome-wide DNA methylation study identifies significant epigenomic changes in osteoarthritic cartilage.
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Academic Article
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Clinical perspectives on lupus genetics: advances and opportunities.
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Academic Article
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Preclinical systemic lupus erythematosus.
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Academic Article
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Barriers And Motivators for Smoking Cessation in Patients With Systemic Lupus Erythematosus (SLE).
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Academic Article
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Regulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
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Academic Article
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Unique Inflammatory Mediators and Specific IgE Levels Distinguish Local from Systemic Reactions after Anthrax Vaccine Adsorbed Vaccination.
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Academic Article
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Combined role of vitamin D status and CYP24A1 in the transition to systemic lupus erythematosus.
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Academic Article
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Dysregulation of innate and adaptive serum mediators precedes systemic lupus erythematosus classification and improves prognostic accuracy of autoantibodies.
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Academic Article
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Association of IFIH1 and pro-inflammatory mediators: Potential new clues in SLE-associated pathogenesis.
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Academic Article
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The Biomarkers of Lupus Disease Study: A Bold Approach May Mitigate Interference of Background Immunosuppressants in Clinical Trials.
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Academic Article
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Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons.
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Academic Article
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Accumulation of Antigen-Driven Lymphoproliferations in Complement Receptor 2/CD21-/low B Cells From Patients With Sjögren's Syndrome.
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Academic Article
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Evidence of Alternative Modes of B Cell Activation Involving Acquired Fab Regions of N-Glycosylation in Antibody-Secreting Cells Infiltrating the Labial Salivary Glands of Patients With Sjögren's Syndrome.
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Academic Article
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A plausibly causal functional lupus-associated risk variant in the STAT1-STAT4 locus.
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Academic Article
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Epstein Barr Virus Interleukin 10 Suppresses Anti-inflammatory Phenotype in Human Monocytes.
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Academic Article
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Autoantibodies against Neurologic Antigens in Nonneurologic Autoimmunity.
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Academic Article
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Bacillus anthracis Edema Toxin Inhibits Efferocytosis in Human Macrophages and Alters Efferocytic Receptor Signaling.
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Academic Article
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TLR engagement induces ARID3a in human blood hematopoietic progenitors and modulates IFNa production.
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Academic Article
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Antigenicity of a recombinant Ro (SS-A) fusion protein.
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Academic Article
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A common autoepitope near the carboxyl terminus of the 60-kD Ro ribonucleoprotein: sequence similarity with a viral protein.
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Academic Article
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Epitope analysis of the major reactive region of the 100-kd protein of PM-Scl autoantigen.
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Academic Article
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Lupus humoral autoimmunity induced in a primate model by short peptide immunization.
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Academic Article
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Immunization as a model for systemic lupus erythematosus.
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Academic Article
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Lupus autoantibodies recognize the product of an alternative open reading frame of SmB/B'.
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Academic Article
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The role of Epstein-Barr virus in systemic lupus erythematosus.
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Academic Article
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Anti-U1A monoclonal antibodies recognize unique epitope targets of U1A which are involved in the binding of U1 RNA.
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Academic Article
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Genetic linkage of systemic lupus erythematosus with chromosome 11q14 (SLEH1) in African-American families stratified by a nucleolar antinuclear antibody pattern.
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Academic Article
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Genome scan stratified by the presence of anti-double-stranded DNA (dsDNA) autoantibody in pedigrees multiplex for systemic lupus erythematosus (SLE) establishes linkages at 19p13.2 (SLED1) and 18q21.1 (SLED2).
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Academic Article
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The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3).
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Academic Article
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Selective small antigenic structures are capable of inducing widespread autoimmunity which closely mimics the humoral fine specificity of human SLE.
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Academic Article
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Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response.
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Academic Article
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Autoimmunity as a result of escape from RNA surveillance.
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Academic Article
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Recent advances and opportunities in research on lupus: environmental influences and mechanisms of disease.
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Academic Article
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Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).
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Academic Article
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Aberrant Epstein-Barr viral infection in systemic lupus erythematosus.
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Academic Article
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A polymorphism within IL21R confers risk for systemic lupus erythematosus.
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Academic Article
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Everyone comes from somewhere: systemic lupus erythematosus and Epstein-Barr virus induction of host interferon and humoral anti-Epstein-Barr nuclear antigen 1 immunity.
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Academic Article
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The role of genetic variation near interferon-kappa in systemic lupus erythematosus.
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Academic Article
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Antiviral immune response in patients with multiple sclerosis, healthy siblings and twins.
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Academic Article
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Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort.
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Academic Article
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Phenotypic associations of genetic susceptibility loci in systemic lupus erythematosus.
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Academic Article
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IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus.
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Academic Article
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Analysis of autosomal genes reveals gene-sex interactions and higher total genetic risk in men with systemic lupus erythematosus.
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Academic Article
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B lymphocyte stimulator levels in systemic lupus erythematosus: higher circulating levels in African American patients and increased production after influenza vaccination in patients with low baseline levels.
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Academic Article
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Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
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Academic Article
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A functional haplotype of UBE2L3 confers risk for systemic lupus erythematosus.
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Academic Article
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Large-scale analysis of tumor necrosis factor a levels in systemic lupus erythematosus.
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Academic Article
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Effects of IRF5 lupus risk haplotype on pathways predicted to influence B cell functions.
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Academic Article
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Lupus and Epstein-Barr.
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Academic Article
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Variation in the ICAM1-ICAM4-ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries.
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Academic Article
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Stochastic humoral immunity to Bacillus anthracis protective antigen: identification of anti-peptide IgG correlating with seroconversion to Lethal Toxin neutralization.
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Academic Article
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Functional characterization of the MECP2/IRAK1 lupus risk haplotype in human T cells and a human MECP2 transgenic mouse.
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Academic Article
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Admixture mapping in lupus identifies multiple functional variants within IFIH1 associated with apoptosis, inflammation, and autoantibody production.
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Academic Article
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Identification of multiple genetic susceptibility loci in Takayasu arteritis.
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Academic Article
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Trans-ancestral studies fine map the SLE-susceptibility locus TNFSF4.
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Academic Article
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Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
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Academic Article
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Vitamin d deficiency in a multiethnic healthy control cohort and altered immune response in vitamin D deficient European-American healthy controls.
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Academic Article
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How should lupus flares be measured? Deconstruction of the safety of estrogen in lupus erythematosus national assessment-systemic lupus erythematosus disease activity index flare index.
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Academic Article
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Association of systemic lupus erythematosus with uranium exposure in a community living near a uranium-processing plant: a nested case-control study.
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Academic Article
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Protective antigen-specific memory B cells persist years after anthrax vaccination and correlate with humoral immunity.
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Academic Article
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Humoral responses to independent vaccinations are correlated in healthy boosted adults.
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Academic Article
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Differential expression of the transcription factor ARID3a in lupus patient hematopoietic progenitor cells.
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Academic Article
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Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
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Academic Article
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Preclinical lupus.
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Academic Article
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Genetics of Lupus Nephritis: Clinical Implications.
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Academic Article
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Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.
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Academic Article
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Transancestral mapping and genetic load in systemic lupus erythematosus.
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Academic Article
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Clinical Efficacy and Safety of Baminercept, a Lymphotoxin ß Receptor Fusion Protein, in Primary Sjögren's Syndrome: Results From a Phase II Randomized, Double-Blind, Placebo-Controlled Trial.
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Academic Article
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Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking.
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Academic Article
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Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.
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Academic Article
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Genetic fine mapping of systemic lupus erythematosus MHC associations in Europeans and African Americans.
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Academic Article
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Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.
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Academic Article
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Latent autoimmunity across disease-specific boundaries in at-risk first-degree relatives of SLE and RA patients.
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Academic Article
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Associations Between Smoking and Systemic Lupus Erythematosus-Related Cytokines and Chemokines Among US Female Nurses.
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Academic Article
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B-cell epitope spreading in autoimmunity.
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Academic Article
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A limited lupus anti-spliceosomal response targets a cross-reactive, proline-rich motif.
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Academic Article
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Genome scan of human systemic lupus erythematosus: evidence for linkage on chromosome 1q in African-American pedigrees.
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Academic Article
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Anti-sm autoantibodies in systemic lupus target highly basic surface structures of complexed spliceosomal autoantigens.
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Academic Article
|
Immunization with peptides from 60 kDa Ro in diverse mouse strains.
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Academic Article
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Stratification of pedigrees multiplex for systemic lupus erythematosus and for self-reported rheumatoid arthritis detects a systemic lupus erythematosus susceptibility gene (SLER1) at 5p15.3.
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Academic Article
|
The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus.
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Academic Article
|
Systemic lupus erythematosus (SLE) and chromosome 16: confirmation of linkage to 16q12-13 and evidence for genetic heterogeneity.
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Academic Article
|
An altered immune response to Epstein-Barr nuclear antigen 1 in pediatric systemic lupus erythematosus.
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Academic Article
|
Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus.
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Academic Article
|
Epstein-Barr virus and systemic lupus erythematosus.
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Academic Article
|
Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
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Academic Article
|
A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus.
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Academic Article
|
Human B cell subsets.
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Academic Article
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Early targets of nuclear RNP humoral autoimmunity in human systemic lupus erythematosus.
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Academic Article
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60 kD Ro and nRNP A frequently initiate human lupus autoimmunity.
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Academic Article
|
Ribosomal P autoantibodies are present before SLE onset and are directed against non-C-terminal peptides.
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Academic Article
|
The lupus family registry and repository.
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Academic Article
|
Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus.
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Academic Article
|
Epitope specificity of myeloperoxidase antibodies: identification of candidate human immunodominant epitopes.
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Academic Article
|
Fine-mapping and transethnic genotyping establish IL2/IL21 genetic association with lupus and localize this genetic effect to IL21.
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Academic Article
|
Limited efficacy of inactivated influenza vaccine in elderly individuals is associated with decreased production of vaccine-specific antibodies.
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Academic Article
|
Identification of novel genetic susceptibility loci in African American lupus patients in a candidate gene association study.
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Academic Article
|
Evaluation of genetic association between an ITGAM non-synonymous SNP (rs1143679) and multiple autoimmune diseases.
|
Academic Article
|
Role of MYH9 and APOL1 in African and non-African populations with lupus nephritis.
|
Academic Article
|
Evaluation of TRAF6 in a large multiancestral lupus cohort.
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Academic Article
|
Fully human monoclonal antibodies from antibody secreting cells after vaccination with Pneumovax®23 are serotype specific and facilitate opsonophagocytosis.
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Academic Article
|
Comparison of autoantibody specificities between traditional and bead-based assays in a large, diverse collection of patients with systemic lupus erythematosus and family members.
|
Academic Article
|
MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus.
|
Academic Article
|
PTPN22 association in systemic lupus erythematosus (SLE) with respect to individual ancestry and clinical sub-phenotypes.
|
Academic Article
|
ABIN1 dysfunction as a genetic basis for lupus nephritis.
|
Academic Article
|
Evidence of dynamically dysregulated gene expression pathways in hyperresponsive B cells from African American lupus patients.
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Academic Article
|
Prolidase deficiency breaks tolerance to lupus-associated antigens.
|
Academic Article
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New perspectives and insights to Asian systemic lupus erythematosus: renal disease, genetic predisposition and disease activity.
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Preferential association of a functional variant in complement receptor 2 with antibodies to double-stranded DNA.
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Disease activity in systemic lupus erythematosus correlates with expression of the transcription factor AT-rich-interactive domain 3A.
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Antibody-secreting cell specificity in labial salivary glands reflects the clinical presentation and serology in patients with Sjögren's syndrome.
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The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
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Ribosomal and immune transcripts associate with relapse in acquired ADAMTS13-deficient thrombotic thrombocytopenic purpura.
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Genome-Wide Association Study in an Amerindian Ancestry Population Reveals Novel Systemic Lupus Erythematosus Risk Loci and the Role of European Admixture.
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Autoantibody-Positive Healthy Individuals Display Unique Immune Profiles That May Regulate Autoimmunity.
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Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification.
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Human effector B lymphocytes express ARID3a and secrete interferon alpha.
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Epstein-Barr virus, cytomegalovirus, and multiple sclerosis susceptibility: A multiethnic study.
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Biomarkers in connective tissue diseases.
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Resequencing Study Confirms That Host Defense and Cell Senescence Gene Variants Contribute to the Risk of Idiopathic Pulmonary Fibrosis.
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Unique Sjögren's syndrome patient subsets defined by molecular features.
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Accelerating Medicines Partnership: Organizational Structure and Preliminary Data From the Phase 1 Studies of Lupus Nephritis.
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PD-1hiCXCR5- T peripheral helper cells promote B cell responses in lupus via MAF and IL-21.
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Shared and unique immune alterations in pre-clinical autoimmunity.
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Emerging evidence of a COVID-19 thrombotic syndrome has treatment implications.
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Deep sequencing reveals a DAP1 regulatory haplotype that potentiates autoimmunity in systemic lupus erythematosus.
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Basic amino acids predominate in the sequential autoantigenic determinants of the small nuclear 70K ribonucleoprotein.
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Sequential autoantigenic determinants of the small nuclear ribonucleoprotein Sm D shared by human lupus autoantibodies and MRL lpr/lpr antibodies.
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Immunoglobulin epitope spreading and autoimmune disease after peptide immunization: Sm B/B'-derived PPPGMRPP and PPPGIRGP induce spliceosome autoimmunity.
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Peptide autoantigenicity of the small nuclear ribonucleoprotein C.
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Lupus humoral autoimmunity after short peptide immunization.
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Grant
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GENETIC ANALYSIS OF EPITOPE SPREADING
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Grant
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Oklahoma High-Throughput Serum Analyte System
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Grant
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GENETIC ANALYSIS OF EPITOPE SPREADING
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Grant
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GENETIC ANALYSIS OF LUPUS AUTOIMMUNITY
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Grant
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Science in a Culture of Mentoring
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Grant
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Science in a Culture of Mentoring
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Grant
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Mechanisms of Lupus Disease Transition and Hydroxychloroquine Immune Modulation
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Multiple Sclerosis Is Rare in Epstein-Barr Virus-Seronegative Children with Central Nervous System Inflammatory Demyelination.
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IgH sequences in common variable immune deficiency reveal altered B cell development and selection.
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T Cell Mediated Conversion of a Non-Anti-La Reactive B Cell to an Autoreactive Anti-La B Cell by Somatic Hypermutation.
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Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus.
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Two Be or Not Two Be: The Nuclear Autoantigen La/SS-B Is Able to Form Dimers and Oligomers in a Redox Dependent Manner.
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Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis.
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Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults.
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Urine Proteomics and Renal Single-Cell Transcriptomics Implicate Interleukin-16 in Lupus Nephritis.
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Editorial: Pathogens, Pathobionts, and Autoimmunity.
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And Yet It Moves: Oxidation of the Nuclear Autoantigen La/SS-B Is the Driving Force for Nucleo-Cytoplasmic Shuttling.
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Antibody Responses to Epstein-Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.
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The intersection of COVID-19 and autoimmunity.
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Immune Response to Enterococcus gallinarum in Lupus Patients Is Associated With a Subset of Lupus-Associated Autoantibodies.
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New-onset IgG autoantibodies in hospitalized patients with COVID-19.
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Safety of procuring research tissue during a clinically indicated kidney biopsy from patients with lupus: data from the Accelerating Medicines Partnership RA/SLE Network.
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Impact of glucocorticoids on the incidence of lupus-related major organ damage: a systematic literature review and meta-regression analysis of longitudinal observational studies.
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Hydrogen-Deuterium Exchange Mass Spectrometry Reveals a Novel Binding Region of a Neutralizing Fully Human Monoclonal Antibody to Anthrax Protective Antigen.
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High incidence of proliferative and membranous nephritis in SLE patients with low proteinuria in the Accelerating Medicines Partnership.
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A High Prevalence of Anti-EBNA1 Heteroantibodies in Systemic Lupus Erythematosus (SLE) Supports Anti-EBNA1 as an Origin for SLE Autoantibodies.
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Genome-wide association study identifies Sjögren's risk loci with functional implications in immune and glandular cells.
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The promise of precision medicine in rheumatology.
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Pre-Clinical Autoimmunity in Lupus Relatives: Self-Reported Questionnaires and Immune Dysregulation Distinguish Relatives Who Develop Incomplete or Classified Lupus From Clinically Unaffected Relatives and Unaffected, Unrelated Individuals.
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Relationship Between a Vitamin D Genetic Risk Score and Autoantibodies Among First-Degree Relatives of Probands With Rheumatoid Arthritis and Systemic Lupus Erythematosus.
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Loss-of-function variants in SAT1 cause X-linked childhood-onset systemic lupus erythematosus.
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Genetic load in incomplete lupus erythematosus.
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Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3.
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Gram-Positive Bacteria Cell Wall Peptidoglycan Polymers Activate Human Dendritic Cells to Produce IL-23 and IL-1? and Promote TH17 Cell Differentiation.
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Researching COVID to Enhance Recovery (RECOVER) adult study protocol: Rationale, objectives, and design.
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CATCH-UP vaccines: protocol for a randomized controlled trial using the multiphase optimization strategy (MOST) framework to evaluate education interventions to increase COVID-19 vaccine uptake in Oklahoma.
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Cerebral small vessel disease pathology in COVID-19 patients: A systematic review.
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Prevalence of autoantibodies to ribosomal P proteins in juvenile-onset systemic lupus erythematosus compared with the adult disease.
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Ancestry-based differences in the immune phenotype are associated with lupus activity.
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Urine proteomic signatures of histological class, activity, chronicity, and treatment response in lupus nephritis.
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Mycophenolate mofetil withdrawal in patients with systemic lupus erythematosus: a multicentre, open-label, randomised controlled trial.
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Longitudinal patterns and predictors of response to standard-of-care therapy in lupus nephritis: data from the Accelerating Medicines Partnership Lupus Network.
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Peptidoglycan from Bacillus anthracis Inhibits Human Macrophage Efferocytosis in Part by Reducing Cell Surface Expression of MERTK and TIM-3.
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Neutrophils isolated from systemic lupus erythematosus patients exhibit a distinct functional phenotype.
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